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crisnatol mesylate

An anticancer drug that interferes with the DNA in cancer cells.
National Institutes of Health

Papers overview

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2004
2004
Microbial metabolism studies of crisnatol (1), a new DNA interca-lator, has resulted in the isolation and characterization of a… 
2004
2004
SummaryFourteen patients with advanced ovarian cancer received a 72 hour infusion of a new DNA intercalator, crisnatol mesylate… 
2004
2004
SummaryCrisnatol mesylate is a rationally designed cytotoxic arylmethylamino-propanediol with broad spectrum cytotoxic activity… 
1999
1999
This Phase I and pharmacological study was performed to assess the feasibility of administering the polycyclic aromatic… 
1997
1997
A total of 26 patients (6 with anaplastic astrocytoma; 20 with glioblastoma) were treated with crisnatol mesylate. All patients… 
1990
1990
The pharmacodynamics of a new series of antitumor DNA intercalators, known as arylmethylaminopropanediols (AMAPs), has been…