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crilvastatin

Known as: 5-Oxo-L-proline, (+-)-cis-3,3,5-trimethylcyclohexyl Ester 
A pyrrolidone non-competitive inhibitor of hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase. Crilvastatin acts by stimulating LDL-cholesterol… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Hydroxymethylglutaryl-CoA Reductase InhibitorsProline
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Reduced cholesterol absorption in hamsters by crilvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
1996
1996
Differences in hypolipidaemic effects of two statins on Hep G2 cells or human hepatocytes in primary culture
1 . The objective of this study was to compare in cultured human hepatocytes or Hep G2 cells, changes in the fate of unesterified… 
1995
1995
Effect of crilvastatin, a new cholesterol lowering agent, on unesterified LDL‐cholesterol metabolism into bile salts by rat isolated hepatocytes
1 The aim of these experiments was to determine the effect of crilvastatin, a new cholesterol lowering agent, on the metabolism… 
1995
1995
Crilvastatin, a new 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, inhibits cholesterol absorption in genetically hypercholesterolemic rats.
1994
1994
Comparative effects of simvastatin and crilvastatin on unesterified LDL cholesterol metabolism into bile salts by primary human hepatocytes
1993
1993
Mechanisms of action in the liver of crilvastatin, a new hydroxymethylglutaryl-coenzyme A reductase inhibitor.
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