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convulxin

Known as: platelet-activating glycoprotein, Crotalus 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Crotalid VenomsLectins, C-Type

Papers overview

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Highly Cited
2006
Highly Cited
2006
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
The snake venom rhodocytin has been reported to bind to integrin alpha2beta1 and glycoprotein (GP) Ibalpha on platelets, but it… Expand
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2006
2006
Crotacetin, a novel snake venom C-type lectin homolog of convulxin, exhibits an unpredictable antimicrobial activity
Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins that are capable of interfering with blood stasis. A very… Expand
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Highly Cited
2003
Highly Cited
2003
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion.
Platelet interaction with exposed adhesive ligands at sites of vascular injury is required to initiate a normal hemostatic… Expand
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Highly Cited
2002
Highly Cited
2002
Association of Fyn and Lyn with the Proline-rich Domain of Glycoprotein VI Regulates Intracellular Signaling*
The glycoprotein VI (GPVI)–Fc receptor (FcR) γ-chain complex, a key activatory receptor for collagen on platelet surface… Expand
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2001
2001
Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.
We have investigated the role of secretion and intracellular signalling events in aggregation induced by the glycoprotein (GP)VI… Expand
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Highly Cited
2000
Highly Cited
2000
Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin.
Factor V (FV) present in platelet alpha-granules has a significant but incompletely understood role in hemostasis. This report… Expand
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Highly Cited
2000
Highly Cited
2000
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
Injuries to the vessel wall and subsequent exposure of collagen from the subendothelial matrix result in thrombus formation. In… Expand
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Highly Cited
2000
Highly Cited
2000
Interaction of Linker for Activation of T Cells with Multiple Adapter Proteins in Platelets Activated by the Glycoprotein VI-selective Ligand, Convulxin*
The snake venom toxin convulxin activates platelets through the collagen receptor glycoprotein VI (GPVI)/Fc receptor γ-chain (FcR… Expand
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Highly Cited
1998
Highly Cited
1998
Physical and Functional Association of the Src Family Kinases Fyn and Lyn with the Collagen Receptor Glycoprotein VI-Fc Receptor γ Chain Complex on Human Platelets
We have previously shown that uncharacterized glycoprotein VI (GPVI), which is constitutively associated and coexpressed with Fc… Expand
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Highly Cited
1997
Highly Cited
1997
Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor*
Convulxin, a powerful platelet activator, was isolated from Crotalus durissus terrificus venom, and 20 amino acid N-terminal… Expand
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