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conformational change

Known as: changes conformational 
 
National Institutes of Health

Papers overview

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2017
2017
Cholesterol-induced conformational changes in the sterol-sensing domain of the Scap protein suggest feedback mechanism to control cholesterol synthesis
Scap is a polytopic protein of endoplasmic reticulum (ER) membranes that transports sterol regulatory element-binding proteins to… Expand
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2016
2016
The molecular mechanism of heme loss from oxidized soluble guanylate cyclase induced by conformational change.
Heme oxidation and loss of soluble guanylate cyclase (sGC) is thought to be an important contributor to the development of… Expand
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Highly Cited
2015
Highly Cited
2015
Structural details of the OxyR peroxide-sensing mechanism
Significance In gram-negative bacteria, OxyR is the master peroxide sensor that regulates the transcription of defense genes in… Expand
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2015
2015
The Regulatory Domain of Squalene Monooxygenase Contains a Re-entrant Loop and Senses Cholesterol via a Conformational Change*
Background: Squalene monooxygenase (SM), a rate-limiting cholesterol synthesis enzyme, is degraded in conditions of excess… Expand
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2015
2015
Functional Dynamics Revealed by the Structure of the SufBCD Complex, a Novel ATP-binding Cassette (ABC) Protein That Serves as a Scaffold for Iron-Sulfur Cluster Biogenesis*
ATP-binding cassette (ABC)-type ATPases are chemomechanical engines involved in diverse biological pathways. Recent genomic… Expand
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2015
2015
Identifying localized changes in large systems: Change-point detection for biomolecular simulations
Significance With data proliferating across many disciplines, data analysts often wish to identify abrupt changes in complex… Expand
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2015
2015
Homologous ligands accommodated by discrete conformations of a buried cavity
Significance Many medicinal chemistry programs change ligands incrementally to explore protein binding and to optimize binding… Expand
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2014
2014
Pigment Interactions in Light-harvesting Complex II in Different Molecular Environments*
Background: Light-harvesting complex II (LHCII) displays different spectroscopic properties in thylakoid membranes and in… Expand
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Highly Cited
2013
Highly Cited
2013
Conformational analysis of the full-length M2 protein of the influenza A virus using solid-state NMR.
The influenza A M2 protein forms a proton channel for virus infection and mediates virus assembly and budding. While extensive… Expand
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2013
2013
Change in single cystathionine β-synthase domain-containing protein from a bent to flat conformation upon adenosine monophosphate binding.
Cystathionine β-synthase (CBS) domains are small intracellular modules that can act as binding domains for adenosine derivatives… Expand
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