comparative genomic analysis

Known as: Genomic Hybridization, Comparative, CGH, Hybridization, Comparative Genome 
Comparative genomic hybridization (CGH) is a technique that allows the detection of losses and gains in DNA copy number across the entire genome… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
PURPOSE To compare the mutational and copy number profiles of primary and metastatic colorectal carcinomas (CRCs) using both… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Medulloblastoma is the most common malignant brain tumor in children. Despite recent improvements in cure rates… (More)
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Highly Cited
2007
Highly Cited
2007
Dyneins are large minus-end-directed microtubule motors. Each dynein contains at least one dynein heavy chain (DHC) and a… (More)
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Highly Cited
2005
Highly Cited
2005
Genomic aberrations in the form of subchromosomal DNA copy number changes are a hallmark of epithelial cancers, including breast… (More)
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Highly Cited
2004
Highly Cited
2004
Array-based comparative genomic hybridization (CGH) measures copy-number variations at multiple loci simultaneously, providing an… (More)
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Highly Cited
2002
Highly Cited
2002
Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a… (More)
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Highly Cited
1999
Highly Cited
1999
A PCR strategy is described for global amplification of DNA from a single eukaryotic cell that enables the comprehensive analysis… (More)
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Highly Cited
1998
Highly Cited
1998
Gene dosage variations occur in many diseases. In cancer, deletions and copy number increases contribute to alterations in the… (More)
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Highly Cited
1997
Highly Cited
1997
Comparative genomic hybridization (CGH) to metaphase chromosomes has been widely used for the genome-wide screening of genomic… (More)
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Highly Cited
1992
Highly Cited
1992
Comparative genomic hybridization produces a map of DNA sequence copy number as a function of chromosomal location throughout the… (More)
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