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columbinic acid

Known as: Fatty Acid 18:3 n-6 cis, cis, trans, Trans,cis,cis-octadeca-5,9,12-trienoic acid, Trans-5, 9, 12-Octadecatirenoic Acid 
A polyunsaturated long-chain fatty acid with an 18-carbon backbone and exactly three double bonds, originating from the 6th, 9th and 13th positions… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

5,9,12-octadecatrienoic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production
Lactobacillus plantarum AKU 1009a effectively transforms linoleic acid to conjugated linoleic acids of cis-9,trans-11… Expand
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1999
1999
Non-methylene-interrupted polyunsaturated fatty acids: effective substitute for arachidonate of phosphatidylinositol.
In mammalian tissues and cells, a characteristic of phosphatidylinositol (PI) is a high abundance of arachidonic acid (AA… Expand
Review
1993
Review
1993
Barrier function regulates epidermal lipid and DNA synthesis
The stratum corneum, the permeability barrier between the internal milieu and the environment, is composed of fibrous protein… Expand
Highly Cited
1992
Highly Cited
1992
Epidermal HMG CoA reductase activity in essential fatty acid deficiency: barrier requirements rather than eicosanoid generation regulate cholesterol synthesis.
We showed previously that the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting enzyme of… Expand
Highly Cited
1987
Highly Cited
1987
Naturally occurring conjugated octadecatrienoic acids are strong inhibitors of prostaglandin biosynthesis.
Fatty acids from natural sources (mostly seed oils) were isolated and assayed for their effect on the bioconversion of… Expand
1986
1986
Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes.
A peripheral component of the delta 6-fatty acid-desaturase system of rat liver microsomes has been isolated from the cytosol by… Expand
1985
1985
The metabolic transformations of columbinic acid and the effect of topical application of the major metabolites on rat skin.
The metabolism of columbinic acid by various fatty acid oxidizing enzyme systems was studied. A cyclooxygenase product, 9-hydroxy… Expand
1985
1985
Physiologic effects of columbinic acid and its metabolites on rat skin.
Columbinic acid and its cyclooxygenase and lipoxygenase metabolites were applied topically to the skin of essential fatty acid… Expand
Highly Cited
1983
Highly Cited
1983
Effect of dietary 18-carbon fatty acids on growth of transplantable mammary adenocarcinomas in mice.
The growth rates of 2 spontaneously developed mammary adenocarcinomas, one in a female C3H mouse and the other in a female BALB/c… Expand
Highly Cited
1981
Highly Cited
1981
Columbinic acid, a new type of essential fatty acid.
 
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