colibactin
National Institutes of Health
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The gut bacterial genotoxin colibactin is linked to the development of colorectal cancer. In the final stages of colibactin’s…
Escherichia coli can harbor genomic pks islands that code for a polyketide-peptide genotoxin known as colibactin. E. coli strains…
Introduction Increasing evidence link the immune microenvironment, microbiota and colorectal cancer (CRC). E. coli pks+ are more…
Introduction: Chronic inflammatory responses within the colonic environment are critical to colorectal cancer (CRC) tumor…
The connection of microbial biosynthetic gene clusters to the small molecule metabolites they encode is central to the discovery…
A genotoxin produced by strains of Escherichia coli induces double-strand breaks in host DNA and promotes chromosome instability…