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codeine-6-glucuronide

Known as: beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
  • B. Kukanich
  • Journal of veterinary pharmacology and…
  • 2010
  • Corpus ID: 20609
The purpose of this study was to determine the pharmacokinetics of codeine and the active metabolites morphine and codeine-6… Expand
Highly Cited
2006
Highly Cited
2006
Our objective was to investigate whether codeine or one of its metabolites contributes substantially to central nervous effects… Expand
Highly Cited
2000
Highly Cited
2000
Abstract Eighty per cent of codeine is conjugated with glucuronic acid to codeine-6-glucuronide. Only 5% of the dose is O… Expand
Highly Cited
1997
Highly Cited
1997
A selective assay of morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), morphine, codeine, codeine-6-glucuronide (C6G… Expand
Highly Cited
1997
Highly Cited
1997
A human UDP-glucuronosyltransferase (UGT) catalyzing the glucuronidation of morphine has been identified. A full length cDNA was… Expand
Highly Cited
1992
Highly Cited
1992
Codeine (30 mg phosphate) was metabolized by eight human volunteers to the following six metabolites: codeine‐6‐glucuronide 81·0… Expand
Highly Cited
1991
Highly Cited
1991
1. The kinetics of codeine and seven of its metabolites codeine-6-glucuronide (C6G), norcodeine (NC), NC-glucuronide (NCG… Expand
Highly Cited
1991
Highly Cited
1991
1. The pharmacokinetics, metabolism and partial clearances of codeine to morphine, norcodeine and codeine-6-glucuronide after… Expand
Highly Cited
1989
Highly Cited
1989
1. A single oral dose of codeine (25 mg) was given to 132 healthy Swedish Caucasians who had previously been phenotyped with… Expand
Highly Cited
1989
Highly Cited
1989
1. The 8 h urinary excretion of codeine and seven of its metabolites was compared in 149 healthy Swedish Caucasians and 133… Expand