Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,239,486 papers from all fields of science
Search
Sign In
Create Free Account
codeine-6-glucuronide
Known as:
beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Broader (1)
Codeine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pharmacokinetics of acetaminophen, codeine, and the codeine metabolites morphine and codeine-6-glucuronide in healthy Greyhound dogs.
B. Kukanich
Journal of veterinary pharmacology and…
2010
Corpus ID: 20609
The purpose of this study was to determine the pharmacokinetics of codeine and the active metabolites morphine and codeine-6…
Expand
Review
2000
Review
2000
Codeine analgesia is due to codeine-6-glucuronide, not morphine.
T. Vree
,
R. V. van Dongen
,
P. M. Koopman-Kimenai
International journal of clinical practice
2000
Corpus ID: 8281493
Eighty per cent of codeine is conjugated with glucuronic acid to codeine-6-glucuronide. Only 5% of the dose is O-demethylated to…
Expand
Highly Cited
2000
Highly Cited
2000
Codeine analgesia is due to codeine-6-glucuronide, not morphine.
Vree Tb
,
Vanarsdel Rt
,
Koop Pm
2000
Corpus ID: 58213749
Abstract Eighty per cent of codeine is conjugated with glucuronic acid to codeine-6-glucuronide. Only 5% of the dose is O…
Expand
Highly Cited
1997
Highly Cited
1997
Human UGT2B7 catalyzes morphine glucuronidation.
B. Coffman
,
G. Rios
,
C. King
,
T. Tephly
Drug metabolism and disposition: the biological…
1997
Corpus ID: 7873288
A human UDP-glucuronosyltransferase (UGT) catalyzing the glucuronidation of morphine has been identified. A full length cDNA was…
Expand
Highly Cited
1992
Highly Cited
1992
Pharmacokinetics and metabolism of codeine in humans
T. Vree
,
C. Wissen
Biopharmaceutics & drug disposition
1992
Corpus ID: 1272306
Codeine (30 mg phosphate) was metabolized by eight human volunteers to the following six metabolites: codeine‐6‐glucuronide 81·0…
Expand
Highly Cited
1991
Highly Cited
1991
Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers.
Z. Chen
,
A. Somogyi
,
G. Reynolds
,
F. Bochner
British journal of clinical pharmacology
1991
Corpus ID: 19877725
1. The pharmacokinetics, metabolism and partial clearances of codeine to morphine, norcodeine and codeine-6-glucuronide after…
Expand
Highly Cited
1991
Highly Cited
1991
Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine.
Q. Yue
,
J. Hasselström
,
J. Svensson
,
J. Säwe
British journal of clinical pharmacology
1991
Corpus ID: 22140613
1. The kinetics of codeine and seven of its metabolites codeine-6-glucuronide (C6G), norcodeine (NC), NC-glucuronide (NCG…
Expand
Highly Cited
1989
Highly Cited
1989
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
Q. Yue
,
J. Svensson
,
C. Alm
,
F. Sjöqvist
,
J. Säwe
British journal of clinical pharmacology
1989
Corpus ID: 41062308
1. A single oral dose of codeine (25 mg) was given to 132 healthy Swedish Caucasians who had previously been phenotyped with…
Expand
Highly Cited
1989
Highly Cited
1989
Interindividual and interethnic differences in the demethylation and glucuronidation of codeine.
Q. Yue
,
J. Svensson
,
C. Alm
,
F. Sjöqvist
,
J. Säwe
British journal of clinical pharmacology
1989
Corpus ID: 22208265
1. The 8 h urinary excretion of codeine and seven of its metabolites was compared in 149 healthy Swedish Caucasians and 133…
Expand
Highly Cited
1970
Highly Cited
1970
Blood levels and urinary excretion of harmine and its metabolites in man and rats.
T. Slotkin
,
V. Distefano
,
W. Au
The Journal of pharmacology and experimental…
1970
Corpus ID: 2441484
This study quantifies blood and urinary levels of harmine and its urinary metabolites (harmol, harmol glucuronide and harmol…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE