FAQ

codeine-6-glucuronide

Known as: beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-yl 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2018
024619702018

Related topics

Related topics

1 relation

Broader (1)

Codeine

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
codeine-6-glucuronide
Codeine

Papers overview

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2010
2010
Pharmacokinetics of acetaminophen, codeine, and the codeine metabolites morphine and codeine-6-glucuronide in healthy Greyhound dogs.
  • B KuKanich
  • Journal of veterinary pharmacology and…
  • 2010
The purpose of this study was to determine the pharmacokinetics of codeine and the active metabolites morphine and codeine-6… (More)
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2006
2006
Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites.
OBJECTIVE Our objective was to investigate whether codeine or one of its metabolites contributes substantially to central nervous… (More)
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2004
2004
Design, chemical synthesis, and biological evaluation of thiosaccharide analogues of morphine- and codeine-6-glucuronide.
A series of 6-beta-thiosaccharide analogues of morphine-6-glucuronide (M6G) and codeine-6-glucuronide (C6G) were synthesized and… (More)
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1997
1997
Analgesic effects of codeine-6-glucuronide after intravenous administration.
Centrally administered codeine glucuronide has been shown to exhibit antinociceptive properties with decreased immunosuppressive… (More)
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Highly Cited
1997
Highly Cited
1997
Human UGT2B7 catalyzes morphine glucuronidation.
A human UDP-glucuronosyltransferase (UGT) catalyzing the glucuronidation of morphine has been identified. A full length cDNA was… (More)
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1997
1997
Determination of morphine and its 3- and 6-glucuronides, codeine, codeine-glucuronide and 6-monoacetylmorphine in body fluids by liquid chromatography atmospheric pressure chemical ionization mass…
A selective assay of morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), morphine, codeine, codeine-6-glucuronide (C6G… (More)
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1991
1991
Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine.
1. The kinetics of codeine and seven of its metabolites codeine-6-glucuronide (C6G), norcodeine (NC), NC-glucuronide (NCG… (More)
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1991
1991
Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers.
1. The pharmacokinetics, metabolism and partial clearances of codeine to morphine, norcodeine and codeine-6-glucuronide after… (More)
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1989
1989
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
1. A single oral dose of codeine (25 mg) was given to 132 healthy Swedish Caucasians who had previously been phenotyped with… (More)
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1989
1989
Interindividual and interethnic differences in the demethylation and glucuronidation of codeine.
1. The 8 h urinary excretion of codeine and seven of its metabolites was compared in 149 healthy Swedish Caucasians and 133… (More)
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