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cobalamin biosynthetic process

Known as: cobalamin biosynthesis, cobalamin anabolism, vitamin B12 biosynthesis 
The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
How I treat cobalamin (vitamin B12) deficiency.
The challenges in medical management of cobalamin deficiency lie in attention to the unique pathophysiology that underlies… Expand
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Review
2008
Review
2008
Causes of and diagnostic approach to methylmalonic acidurias
SummarySeveral mutant genetic classes that cause isolated methylmalonic acidurias (MMAuria) are known based on biochemical… Expand
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Highly Cited
2007
Highly Cited
2007
Identification of novel genes in genomic islands that contribute to Salmonella typhimurium replication in macrophages.
Salmonella enterica serovar Typhimurium (S. typhimurium) survives and proliferates within macrophage cells. A mutant library of… Expand
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Highly Cited
2006
Highly Cited
2006
The Complete Genome Sequence and Comparative Genome Analysis of the High Pathogenicity Yersinia enterocolitica Strain 8081
The human enteropathogen, Yersinia enterocolitica, is a significant link in the range of Yersinia pathologies extending from mild… Expand
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Highly Cited
2005
Highly Cited
2005
Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum.
DNA microarray analysis of Clostridium acetobutylicum was used to examine the genomic-scale gene expression changes during the… Expand
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Highly Cited
2004
Highly Cited
2004
Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes.
Recent studies have begun to reveal that numerous fundamental metabolic pathways in bacteria are regulated by riboswitches… Expand
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Highly Cited
2003
Highly Cited
2003
Regulation of the vitamin B12 metabolism and transport in bacteria by a conserved RNA structural element.
Cobalamin in the form of adenosylcobalamin (Ado-CBL) is known to repress expression of genes for vitamin B(12) biosynthesis and… Expand
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Review
2000
Review
2000
Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
Abstract. The biosynthesis of cobalamin (vitamin B12) is described, revealing how the concerted action of around 30 enzyme… Expand
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Review
1998
Review
1998
Remethylation defects: guidelines for clinical diagnosis and treatment
Abstract The main remethylation defects include disorders which all have defective methionine synthesis in common… Expand
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Highly Cited
1997
Highly Cited
1997
Propanediol utilization genes (pdu) of Salmonella typhimurium: three genes for the propanediol dehydratase.
The propanediol utilization (pdu) operon of Salmonella typhimurium encodes proteins required for the catabolism of propanediol… Expand
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