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cobalamin biosynthetic process

Known as: cobalamin biosynthesis, cobalamin anabolism, vitamin B12 biosynthesis 
The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a… 
National Institutes of Health

Papers overview

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1997
1997
Sequence of a 189-kb segment of the chromosome of Rhodobacter capsulatus SB1003.
Cosmids from the 1A3-1A10 region of the complete miniset were individually subcloned by using the vector M13 mp18. Sequences of… 
1996
1996
Synthesis and nca-radioiodination of arylstannyl-cobalamin conjugates. Evaluation of aryliodo-cobalamin conjugate binding to transcobalamin II and biodistribution in mice.
A new method of preparing radiolabeled cobalamin derivatives has been developed. The method involves the use of cobalamin-tri-n… 
1993
1993
Homology of pyridoxal-5'-phosphate-dependent aminotransferases with the cobC (cobalamin synthesis), nifS (nitrogen fixation), pabC (p-aminobenzoate synthesis) and malY (abolishing endogenous…
Bacterial deletion mutants have indicated that the gene products of cobC, nifS, pabC and malY participate in important metabolic… 
1992
1992
Enzymatic synthesis and structure of precorrin-3, a trimethyldipyrrocorphin intermediate in vitamin B12 biosynthesis.
The trimethylated intermediate of vitamin B12 (corrin) biosynthesis, precorrin-3, was produced from various 13C-enriched… 
1986
1986
Cloning of multiple genes involved with cobalamin (Vitamin B12) biosynthesis in Bacillus megaterium
An effective shotgun cloning procedure was developed for Bacillus megaterium by amplifying gene libraries in Bacillus subtilis… 
1985
1985
Amidation of, and (R)-1-amino-2-propanol attachment to, the corrin ring during vitamin B-12 biosynthesis by Clostridium tetanomorphum extracts.
Highly Cited
1978
Highly Cited
1978
Effect of folate and cobalamin compounds on the deoxyuridine suppression test in vitamin B12 and folate deficiency.
In vitro, deoxyuridine (dU) failed to block the incorporation of 3H-thymidine into bone marrow from 11 cases of vitamin B,2… 
1970
1970
Escherichia coli B 5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase: catalysis by a reconstituted methyl-14C-cobalamin holoenzyme and the function of S-adenosyl-l-methionine.
Highly Cited
1969
Highly Cited
1969
Patterns of plasma cobalamins in control subjects and in cases of vitamin B12 deficiency
A method for thin-layer chromatography and bioautography of plasma cobalamins is described. It requires only 5 ml of blood… 
1965
1965
Conversion of Cyano- and Hydroxo-cobalamin in vivo into Co-enzyme Form of Vitamin B12 in the Rat
SINCE 5,6-dimethylbenzimidazolyl cobamide co-enzyme (DBCC) was shown to be one of the active forms of vitamin B12 by Barker et al… 
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