Share This Author
Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol.
Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus.
Structure of the Methanococcus jannaschii Mevalonate Kinase, a Member of the GHMP Kinase Superfamily*
- Dong Yang, L. Shipman, C. Roessner, A. Scott, J. Sacchettini
- Biology, ChemistryThe Journal of Biological Chemistry
- 15 March 2002
Analysis of the MVK model in the context of the other members of the GHMP kinase family offers the opportunity to understand both the mechanism of these enzymes and the structural details that may lead to the design of novel drugs.
Overcoming product inhibition of S-Adenosyl-L-methionine (SAM) synthetase: Preparation of SAM on the 30 mM scale
Identification and Characterization of a Novel Vitamin B12 (Cobalamin) Biosynthetic Enzyme (CobZ) from Rhodobacter capsulatus, Containing Flavin, Heme, and Fe-S Cofactors*
Recombinant overproduction of Orf663, now renamed CobZ, allowed the characterization of a novel cofactor-rich protein, housing two Fe-S centers, a flavin, and a heme group, which like B12 itself is a modified tetrapyrrole.
Crystal structure of precorrin-8x methyl mutase.
Enzymatic synthesis of S-adenosyl-L-methionine on the preparative scale.
The Escherichia coli cysG gene encodes the multifunctional protein, siroheme synthase
Gene dissection demonstrates that the Escherichia coli cysG gene encodes a multifunctional protein.
- M. Warren, E. Bolt, C. Roessner, A. Scott, J. Spencer, S. Woodcock
- Biology, ChemistryThe Biochemical journal
- 15 September 1994
The evidence presented in this paper suggests that the CysG protein is a multifunctional protein involved in SAM-dependent methylation, pyridine dinucleotide dependent dehydrogenation and ferrochelation.
Biosynthesis of cobalamin (vitamin B(12)).
The biosynthesis of vitamin B(12) is summarized, emphasizing the differences observed between the aerobic and anaerobic pathways. The biosynthetic route to adenosylcobalamin from its five-carbon…