coagulation factor IX, human

Known as: Factor IX, factor ix (human), Factor 9 
Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation… (More)
National Institutes of Health

Related topics

Related topics

23 relations
Blood coagulationCalcium BindingCoagulation factor IX measurementEGF-Like Domain
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Narrower (4)

KcentraMononineRixubisnonacog alfa

Broader (1)

factor IX

Papers overview

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Highly Cited
2012
Highly Cited
2012
An Immune-Related Gene Evolved into the Master Sex-Determining Gene in Rainbow Trout, Oncorhynchus mykiss
Since the discovery of Sry in mammals [1, 2], few other master sex-determining genes have been identified in vertebrates [3-7… (More)
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Review
2008
Review
2008
Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality.
Oocyte quality is a key limiting factor in female fertility, yet we have a poor understanding of what constitutes oocyte quality… (More)
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Highly Cited
2007
Highly Cited
2007
Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells.
Oocyte-derived bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) are key regulators of follicular… (More)
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Highly Cited
2006
Highly Cited
2006
Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination
The genes encoding members of the wingless-related MMTV integration site (WNT) and fibroblast growth factor (FGF) families… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries).
Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting ewes with exceptionally high litter… (More)
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Highly Cited
2003
Highly Cited
2003
Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer.
Gene replacement therapy is an attractive approach for treatment of genetic disease, but may be complicated by the risk of a… (More)
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Highly Cited
2002
Highly Cited
2002
Anti-Müllerian Hormone Inhibits Initiation of Primordial Follicle Growth in the Mouse Ovary.
Department of Endocrinology and Reproduction (A.L.L.D., M.J.G.G., P.K., J.Th.J.U., J.A.G., A.P.N.T.), Faculty of Medicine and… (More)
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Highly Cited
2001
Highly Cited
2001
Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function.
Knockout mouse technology has been used over the last decade to define the essential roles of ovarian-expressed genes and uncover… (More)
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Highly Cited
2001
Highly Cited
2001
Male-to-Female Sex Reversal in Mice Lacking Fibroblast Growth Factor 9
Fgfs direct embryogenesis of several organs, including the lung, limb, and anterior pituitary. Here we report male-to-female sex… (More)
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Highly Cited
1998
Highly Cited
1998
The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes.
We have taken advantage of the sequence relationships among the bone morphogenetic proteins (BMPs) to identify the mouse Bmp15… (More)
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