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clinprost

Known as: isocarbacyclin methyl ester 
 
National Institutes of Health

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TEI 9090

Papers overview

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2013
2013
Sequential Pd(0)-, Rh(I)-, and Ru(II)-catalyzed reactions in a nine-step synthesis of clinprost.
A step-economical synthesis of clinprost is reported that concludes with 3 different transition metal-catalyzed reactions: Pd… Expand
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1997
1997
Protective effect of a prostaglandin I2 analog, TEI-7165, on ischemic neuronal damage in gerbils
TTC-909 (Clinprost), a chemically stable PGI2 analog, isocarbacyclin methyl ester (TEI-9090 or Clinprost) incorporated in lipid… Expand
1996
1996
Neuroprotective effect of TTC-909, an isocarbacyclin methyl ester incorporated in lipid microspheres, on hippocampal delayed neuronal death of stroke-prone spontaneously hypertensive rats.
TTC-909 is a newly developed isocarbacyclin methyl ester (TEI-9090) incorporated in lipid microspheres. The neuroprotective… Expand
1996
1996
Blood‐brain‐barrier Transport of Lipid Microspheres Containing Clinprost, a Prostaglandin I2 Analogue
Because the permeability of the blood‐brain barrier to lipid microspheres (LMs) has not hitherto been demonstrated, blood‐brain… Expand
Highly Cited
1995
Highly Cited
1995
Species differences in hydrolysis of isocarbacyclin methyl ester (TEI-9090) by blood esterases.
Species differences in the hydrolysis of isocarbacyclin methyl ester (TEI-9090) in whole blood and in its separated components… Expand
1995
1995
Effect of isocarbacyclin methyl ester incorporated in lipid microspheres on experimental models of peripheral obstructive disease.
The effect of TTC-909 (isocarbacyclin methyl ester (CAS 88931-51-5, TEI-9090) incorporated into lipid microspheres) on… Expand
1995
1995
Binding affinities of isocarbacyclin methyl ester and its free acid to prostanoid receptors.
The binding affinities of isocarbacyclin methyl ester (CAS 88931-51-5, TEI-9090) and its free acid (CAS 88911-35-7, TEI-7165) to… Expand
1995
1995
Vasorelaxant effect of isocarbacyclin methyl ester incorporated into lipid microspheres on isolated canine arteries.
TTC-909 is a preparation of isocarbacyclin methyl ester (CAS 88931-51-5, TEI-9090) incorporated into lipid microspheres. The… Expand
1994
1994
Determination of Protein Binding of a Highly Lipophilic Drug, Isocarbacyclin Methyl Ester (TEI‐9090), Using a Polydimethylsiloxane‐coated Glass Beads Assay
Abstract— An adsorption technique with polydimethylsiloxane‐coated glass beads (PDMS‐GB) was developed to determine the protein… Expand
1987
1987
Effect of PGI2 on transcellular transport of fluorescein dextran through an arterial endothelial monolayer.
The effects of prostacyclin (PGI2) and stable derivatives of PGI2, such as isocarbacyclin (PGI2 deriv. (A] and isocarbacyclin… Expand
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