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cizolirtine

Known as: 1-methyl-5-((2,N,N-dimethylaminoethoxy)(phenyl)methyl)-1H-pyrazole citrate, Ethanamine, N,N-dimethyl-2-((1-methyl-1H-pyrazol-5-yl)phenylmethoxy)-, 2-hydroxy-1,2,3-propanetricarboxylate 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

E 4018

Broader (1)

Pyrazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Cizolirtine citrate is safe and effective for treating urinary incontinence secondary to overactive bladder: a phase 2 proof-of-concept study.
2009
2009
Cizolirtine citrate, an effective treatment for symptomatic patients with urinary incontinence secondary to overactive bladder: a pilot dose-finding study.
2007
2007
Evidence for adenosine- and serotonin-mediated antihyperalgesic effects of cizolirtine in rats suffering from diabetic neuropathy
2003
2003
Effects of the novel analgesic, cizolirtine, in a rat model of neuropathic pain
2001
2001
Cizolirtine Citrate (E-4018) in the Treatment of Chronic Neuropathic Pain
Summary This study was performed to determine the efficacy and safety of oral cizolirtine citrate, a novel agent, in the… 
Review
2001
Review
2001
Cizolirtine. Laboratorios Dr Esteve.
Cizolirtine is a centrally-acting analgesic that is under development by Esteve for the potential treatment of pain [171179]. In… 
2001
2001
The novel analgesic, cizolirtine, inhibits the spinal release of substance P and CGRP in rats
2000
2000
Pharmacology of cizolirtine: a new analgesic agent.
Cizolirtine citrate (E-4018) is a new analgesic agent with antinociceptive activity against phenylquinone (ED50 33.7 mg/kg) and… 
2000
2000
Dose Response and Safety of Cizolirtine Citrate (E-4018) in Patients with Pain Following Extraction of Third Molars
Summary The objectives of this study were to determine the dose response and safety of the oral analgesic cizolirtine citrate (E… 
1999
1999
Chiral discrimination of the analgesic cizolirtine by using cyclodextrins: A (1)H NMR study on the solution structures of their host-guest complexes.
The use of four cyclodextrins (three native and one beta-CD derivative) as NMR chiral solvating agents to resolve the enantiomers… 
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