cipargamin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2014-2018
012320142018

Papers overview

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2018
2018
For an increasing number of antimalarial agents identified in high throughput phenotypic screens there is evidence that they… (More)
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2017
2017
The MIC of an antimalarial drug for a particular infection is the drug level associated with a net parasite multiplication rate… (More)
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2017
2017
Directed evolution is an experimental strat­ egy that is used to mimic natural selection to generate a library of biomolecule… (More)
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2016
2016
The spiroindolones, a new class of antimalarial medicines discovered in a cellular screen, are rendered less active by mutations… (More)
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2016
2016
KAE609 [(1'R,3'S)-5,7'-dichloro-6'-fluoro-3'-methyl-2',3',4',9'-tetrahydrospiro[indoline-3,1'-pyridol[3,4-b]indol]-2-one] is a… (More)
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Review
2015
Review
2015
The intraerythrocytic malaria parasite, Plasmodium falciparum, maintains a low cytosolic Na(+) concentration and the plasma… (More)
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2015
2015
KAE609 represents a new class of potent, fast-acting, schizonticidal antimalarials. This study investigated the safety and… (More)
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2015
2015
A direct catalytic asymmetric alkynylation protocol is applied to provide the requisite enantioenriched propargylic α-tertiary… (More)
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2014
2014
This first-in-human randomized, double-blind, placebo-controlled, ascending-single and -multiple oral dose study was designed to… (More)
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