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NITD 609

Known as: NITD-609, NITD609 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
  • H. Turner
  • Future medicinal chemistry
  • 2016
  • Corpus ID: 42300969
Malaria is caused by the Plasmodium parasite and is a major health problem leading to many deaths worldwide. Lack of a vaccine… Expand
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Highly Cited
2015
Highly Cited
2015
An asymmetric aza-Diels-Alder reaction of 3-vinylindoles with isatin-derived ketimines has been developed. A series of… Expand
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2015
2015
A direct catalytic asymmetric alkynylation protocol is applied to provide the requisite enantioenriched propargylic α-tertiary… Expand
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Highly Cited
2014
Highly Cited
2014
ABSTRACT This first-in-human randomized, double-blind, placebo-controlled, ascending-single and -multiple oral dose study was… Expand
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2014
2014
ABSTRACT To achieve malarial elimination, we must employ interventions that reduce the exposure of human populations to… Expand
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2013
2013
ABSTRACT Here, we show that spiroindolone, an effective treatment for plasmodia, is also active against Toxoplasma gondii… Expand
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Review
2012
Review
2012
The need for new drugs against tropical parasites such as Plasmodium falciparum and Trypanosoma brucei is persistent since… Expand
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Highly Cited
2012
Highly Cited
2012
ABSTRACT The global malaria agenda has undergone a reorientation from control of clinical cases to entirely eradicating malaria… Expand
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2012
2012
During the synthesis of the new antimalarial drug candidate NITD609, a high degree of diastereoselectivity was observed in the… Expand
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2010
2010
A return to traditional screening methods has rapidly produced a candidate malaria drug. Every so often, the tide turns in a… Expand