NITD 609

Known as: NITD-609, NITD609 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2016
02420102016

Papers overview

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2017
2017
Directed evolution is an experimental strat­ egy that is used to mimic natural selection to generate a library of biomolecule… (More)
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Review
2016
Review
2016
Malaria is caused by the Plasmodium parasite and is a major health problem leading to many deaths worldwide. Lack of a vaccine… (More)
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2015
2015
To achieve malarial elimination, we must employ interventions that reduce the exposure of human populations to infectious… (More)
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2015
2015
An asymmetric aza-Diels-Alder reaction of 3-vinylindoles with isatin-derived ketimines has been developed. A series of… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND KAE609 (cipargamin; formerly NITD609, Novartis Institute for Tropical Diseases) is a new synthetic antimalarial… (More)
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2014
2014
This first-in-human randomized, double-blind, placebo-controlled, ascending-single and -multiple oral dose study was designed to… (More)
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2014
2014
Here, we show that spiroindolone, an effective treatment for plasmodia, is also active against Toxoplasma gondii tachyzoites. In… (More)
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2012
2012
The global malaria agenda has undergone a reorientation from control of clinical cases to entirely eradicating malaria. For that… (More)
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2012
2012
During the synthesis of the new antimalarial drug candidate NITD609, a high degree of diastereoselectivity was observed in the… (More)
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Highly Cited
2010
Highly Cited
2010
Recent reports of increased tolerance to artemisinin derivatives--the most recently adopted class of antimalarials--have prompted… (More)
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