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cinnoline

National Institutes of Health

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Heterocyclic Compounds, 2-Ring
hexahydrocinnoline

Papers overview

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2016
2016
Expedient synthesis of new cinnoline diones by Ru-catalyzed regioselective unexpected deoxygenation-oxidative annulation of propargyl alcohols with phthalazinones and pyridazinones.
Ruthenium-catalyzed simple, cascade and one-pot synthesis of cinnoline-fused diones has been carried out by the C-H activation of… 
2014
2014
Structural findings of cinnolines as anti-schizophrenic PDE10A inhibitors through comparative chemometric modeling
Schizophrenia is a complex psychiatric disorder associated with the distortion of striatopallidal neurotransmission of central… 
2013
2013
Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507.
2011
2011
Discovery of novel anti-inflammatory drug-like compounds by aligning in silico and in vivo screening: the nitroindazolinone chemotype.
2010
2010
Developing dual functional allosteric modulators of GABA(A) receptors.
2000
2000
On the chemistry of cinnoline III: Condensation reactions of (4-amino-cinnolin-3-yl)-phenyl-menthanone and 4-amino-3-cinnoline-carbonitrile
(4-Amino-cinnolin-3-yl)-phenyl-methanone condensed with malononitrile, ethyl cyanoacetate, acetylacetone, ethyl acetoacetate… 
1998
1998
Metabolism of cinnoline to N-oxidation products by Cunninghamella elegans and Aspergillus niger
Cultures of the fungi Cunninghamella elegans and Aspergillus niger were grown in fluid Sabouraud medium at 28°C for 3 days and… 
1997
1997
o-Nitroaryl-bis(5-methylfur-2-yl)methanes as Versatile Synthons for the Synthesis of Nitrogen-Containing Heterocycles
2-Nitroaryldifurylmethanes 1a and 1b, readily available by condensation of 2-nitrobenzaldehyde and 6-nitroveratraldehyde with 2… 
1996
1996
Quinaldine 4-oxidase from Arthrobacter sp. Rü61a, a versatile procaryotic molybdenum-containing hydroxylase active towards N-containing heterocyclic compounds and aromatic aldehydes.
Quinaldine 4-oxidase from Arthrobacter sp. Rü61a, an inducible molybdenum-containing hydroxylase, was purified to homogeneity by… 
1949
1949
A New Synthesis of Cinnoline Derivatives
IN connexion with an investigation on the elaboration of the Coffey1 synthesis of 1-ketotetra-hydrocarbazoles, a study of the… 
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