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cicaprost

Known as: 13,14-didehydro-16,20-dimethyl-3-oxa-18,18,19,19-tetradehydro-6-carbaprostaglandin I2, 5-(7-hydroxy-6-(3-hydroxy-4-methylnona-1,6-diynyl)-bicyclo(3.3.0)octan-3-yliden)-3-oxapentanoic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Signaling through the PGI2 receptor (IP) has been shown to inhibit inflammatory responses in mouse models of respiratory… Expand
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Highly Cited
2006
Highly Cited
2006
Background:  Mast cells cultured from human peripheral blood have been widely used to study human mast cell function. Prostanoids… Expand
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2006
2006
The current study examined the utility of the recently described prostacyclin (prostanoid IP) receptor antagonist RO1138452 (2‐(4… Expand
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2004
2004
Long-term infusion of prostacyclin, or its analogs, is an effective treatment for severe pulmonary arterial hypertension. However… Expand
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Highly Cited
2004
Highly Cited
2004
Dilatation of the cerebral vasculature is recognised to be involved in the pathophysiology of migraine. Furthermore, elevated… Expand
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Highly Cited
2002
Highly Cited
2002
We determined the distribution of ETA and ETB receptors in pulmonary arteries from pulmonary hypertensive patients and control… Expand
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Highly Cited
2001
Highly Cited
2001
The prostacyclin receptor (IP) is primarily coupled to Gαs-dependent activation of adenylyl cyclase; however, a number of studies… Expand
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Highly Cited
1998
Highly Cited
1998
Interleukin‐10 (IL‐10) and tumor necrosis factor (TNF) exert key roles in some acute and chronic inflammatory diseases. In this… Expand
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Highly Cited
1997
Highly Cited
1997
1 The prostanoid receptor(s) that mediates inhibition of bacterial lipopolysaccharide (LPS)‐induced tumour necrosis factor‐α (TNF… Expand
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Highly Cited
1993
Highly Cited
1993
1 Prostanoid receptors present on the pregnant human myometrium in vitro have been characterized according to the receptor… Expand
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