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cicaprost
Known as:
13,14-didehydro-16,20-dimethyl-3-oxa-18,18,19,19-tetradehydro-6-carbaprostaglandin I2
, 5-(7-hydroxy-6-(3-hydroxy-4-methylnona-1,6-diynyl)-bicyclo(3.3.0)octan-3-yliden)-3-oxapentanoic acid
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Antineoplastic Agents
Epoprostenol
Narrower (1)
ZK 96480
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Agonist-dependent internalization and trafficking of the human prostacyclin receptor: A direct role for Rab5a GTPase
M. O'Keeffe
,
H. Reid
,
B. Kinsella
Biochimica et Biophysica Acta
2008
Corpus ID: 23235597
2006
2006
Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells.
H. Wise
European Journal of Pharmacology
2006
Corpus ID: 10921302
2004
2004
Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase.
A. Sobolewski
,
K. Jourdan
,
P. Upton
,
L. Long
,
N. Morrell
American Journal of Physiology - Lung cellular…
2004
Corpus ID: 8720926
Long-term infusion of prostacyclin, or its analogs, is an effective treatment for severe pulmonary arterial hypertension. However…
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Highly Cited
2004
Highly Cited
2004
Dimerization of the Human Receptors for Prostacyclin and Thromboxane Facilitates Thromboxane Receptor-mediated cAMP Generation*
Stephen J. Wilson
,
A. Roche
,
E. Kostetskaia
,
E. Smyth
Journal of Biological Chemistry
2004
Corpus ID: 26016239
Prostacyclin (PGI2) and thromboxane (TxA2) are biological opposites; PGI2, a vasodilator and inhibitor of platelet aggregation…
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2003
2003
Asymmetric synthesis of the highly potent anti-metastatic prostacyclin analogue cicaprost and its isomer isocicaprost.
Marco Lerm
,
H. Gais
,
K. Cheng
,
C. Vermeeren
Journal of the American Chemical Society
2003
Corpus ID: 25854533
An asymmetric synthesis of the anti-metastatic prostacyclin analogue cicaprost and a formal one of its isomer isocicaprost by a…
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2001
2001
Role of endogenous prostacyclin in gastric ulcerogenic and healing responses—a study using IP-receptor knockout mice
K. Takeuchi
,
S. Kato
,
Y. Ogawa
,
K. Kanatsu
,
M. Umeda
Journal of Physiology - Paris
2001
Corpus ID: 40235452
1997
1997
Inhibition of metastasis by cicaprost in rats with established SMT2A mammary carcinoma growth.
M. Schirner
,
M. Schneider
Cancer Detection and Prevention
1997
Corpus ID: 42720055
Cicaprost, a stable prostacyclin analog has been shown to be antimetastatically active in a series of metastasizing rodent tumors…
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1996
1996
The inhibitory effects of non-prostanoid prostacyclin mimetics on rat neutrophil function.
H. Wise
Prostaglandins, Leukotrienes and Essential Fatty…
1996
Corpus ID: 26912761
Highly Cited
1994
Highly Cited
1994
Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system.
O. Nakagawa
,
I. Tanaka
,
+7 authors
K. Nakao
Circulation
1994
Corpus ID: 14374579
BACKGROUND Prostacyclin elicits a potent vasodilation and inhibition of platelet aggregation through binding to its membrane…
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1993
1993
Arachidonic acid stimulates interleukin-6 release from rat peritoneal macrophages in vitro: evidence for a prostacyclin-dependent mechanism.
C. Holladay
,
R. Wright
,
B. Spangelo
Prostaglandins, Leukotrienes and Essential Fatty…
1993
Corpus ID: 25093395
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