cicaprost

Known as: 13,14-didehydro-16,20-dimethyl-3-oxa-18,18,19,19-tetradehydro-6-carbaprostaglandin I2, 5-(7-hydroxy-6-(3-hydroxy-4-methylnona-1,6-diynyl)-bicyclo(3.3.0)octan-3-yliden)-3-oxapentanoic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Signaling through the PGI(2) receptor (IP) has been shown to inhibit inflammatory responses in mouse models of respiratory… (More)
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2006
2006
OBJECTIVE We investigated the role of the inward rectifier potassium (KIR) channel and the cyclic AMP-dependent pathway in… (More)
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Highly Cited
2002
Highly Cited
2002
We determined the distribution of ET(A) and ET(B) receptors in pulmonary arteries from pulmonary hypertensive patients and… (More)
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1999
1999
1. To characterize the prostanoid receptors on human pulmonary smooth muscle involved in vasodilatations, isolated arteries and… (More)
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Highly Cited
1998
Highly Cited
1998
Interleukin-10 (IL-10) and tumor necrosis factor (TNF) exert key roles in some acute and chronic inflammatory diseases. In this… (More)
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1997
1997
We have studied the effects of chronic therapy with cicaprost (a PGI2 analog), fosinopril (a converting enzyme inhibitor), and… (More)
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1993
1993
Cicaprost is a new synthetic prostacylin analogue which is metabolically stable and bioavailable after oral administration; in… (More)
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1993
1993
Cicaprost, a stable prostacyclin analogue with antimetastatic potential, was investigated as regards its effect on the tumor… (More)
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1992
1992
Iloprost and cicaprost are two PGI2-mimetics, which are chemically stable and highly pharmacologically potent. Both compounds… (More)
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1989
1989
Cicaprost (5-[(E)-(1S,5S,6S,7R)-7-hydroxy-6-[(3S,4S)-3-hydroxy-4-methylnona- 1,6- diinyl]-bicyclo[3.3.0]octan-3-yliden]-3… (More)
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