cicaprost

Signaling through the PGI2 receptor (IP) has been shown to inhibit inflammatory responses in mouse models of respiratory… Expand

Background:  Mast cells cultured from human peripheral blood have been widely used to study human mast cell function. Prostanoids… Expand

The current study examined the utility of the recently described prostacyclin (prostanoid IP) receptor antagonist RO1138452 (2‐(4… Expand

Long-term infusion of prostacyclin, or its analogs, is an effective treatment for severe pulmonary arterial hypertension. However… Expand

Dilatation of the cerebral vasculature is recognised to be involved in the pathophysiology of migraine. Furthermore, elevated… Expand

We determined the distribution of ETA and ETB receptors in pulmonary arteries from pulmonary hypertensive patients and control… Expand

The prostacyclin receptor (IP) is primarily coupled to Gαs-dependent activation of adenylyl cyclase; however, a number of studies… Expand

Interleukin‐10 (IL‐10) and tumor necrosis factor (TNF) exert key roles in some acute and chronic inflammatory diseases. In this… Expand

1 The prostanoid receptor(s) that mediates inhibition of bacterial lipopolysaccharide (LPS)‐induced tumour necrosis factor‐α (TNF… Expand

1 Prostanoid receptors present on the pregnant human myometrium in vitro have been characterized according to the receptor… Expand