chymase activity

Ang I-converting enzyme (ACE) inhibitors are widely believed to suppress the deleterious cardiac effects of Ang II by inhibiting… (More)

Secretory leukocyte protease inhibitor (SLPI) is a protease inhibitor of the whey acidic protein-like family inhibiting chymase… (More)

OBJECTIVES Recent studies have demonstrated that hamsters, like humans, possess both angiotensin converting enzyme (ACE)- and… (More)

Dipeptidyl peptidase I (DPPI) is the sole activator in vivo of several granule-associated serine proteases of cytotoxic… (More)

We cloned a rat vascular chymase (RVCH) from smooth muscle cells (SMCs) that converts angiotensin I to II and is up-regulated in… (More)

BACKGROUND Mast cells (MCs) are known to participate in various types of chronic disease, but their role in chronic renal… (More)

Chymases are highly basic chymotrypsin-like serine proteases expressed exclusively by mast cells. Large amounts of chymases… (More)

The current study examined the contributions of angiotensin-converting enzyme (ACE) vs. chymase to angiotensin II (ANG II… (More)

The number and distribution of mast cells in nonlesional and lesional skin samples from 13 psoriatic patients were analyzed… (More)

The ability of plasma proteinase inhibitors to inactivate human chymase, a chymotrypsin-like proteinase stored within mast cell… (More)