chromatin binding

Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
0204019692018

Papers overview

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Highly Cited
2013
Highly Cited
2013
Bromodomain-containing protein 4 (Brd4) is an epigenetic reader and transcriptional regulator recently identified as a cancer… (More)
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Highly Cited
2012
Highly Cited
2012
Live-cell measurement of protein binding to chromatin allows probing cellular biochemistry in physiological conditions, which are… (More)
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Highly Cited
2010
Highly Cited
2010
Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip… (More)
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Highly Cited
2006
Highly Cited
2006
Polycomb group (PcG) proteins maintain transcriptional repression of developmentally important genes and have been implicated in… (More)
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Highly Cited
2006
Highly Cited
2006
Cohesin is a multisubunit protein complex that links sister chromatids from replication until segregation. The lack of obvious… (More)
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Highly Cited
2005
Highly Cited
2005
Estrogen plays an essential physiologic role in reproduction and a pathologic one in breast cancer. The completion of the human… (More)
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Highly Cited
2001
Highly Cited
2001
The tumor suppressor protein, p53, plays a critical role in mediating cellular response to stress signals by regulating genes… (More)
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Highly Cited
2001
Highly Cited
2001
Mammalian interphase and mitotic cells were analyzed for their cation composition using a three-dimensional high resolution… (More)
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Highly Cited
1999
Highly Cited
1999
A novel human gene (PLU-1) has been identified which shows a highly restricted expression in normal adult tissues but which is… (More)
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Highly Cited
1995
Highly Cited
1995
Interaction of chromatin with the nuclear envelope and lamina is thought to help determine higher order chromosome organization… (More)
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