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cholestenone 5-alpha-reductase activity

Known as: 3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity, 3-oxosteroid 5alpha-reductase activity, testosterone delta4-hydrogenase activity 
Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH. [EC:1.3.1.22, RHEA:24555]
National Institutes of Health

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Broader (1)

3-oxo-5-alpha-steroid 4-dehydrogenase activity

Papers overview

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1982
1982
Inactivation of delta5-3-ketosteroid isomerase(s) from beef adrenal cortex by beta, gamma-acetylenic ketosteroids.
The beta, gamma-acetylenic ketosteroids, 5-10-seco-19-norpregn-5-yne-3,-10,20-trione approximately 1 and 5,10-secoestr-5-yne-3,10… 
1978
1978
Hormonal regulation of 4-ene-5alpha-reductase activity in prepubertal rat ovaries.
1977
1977
Influences of central acting drugs on delta4-3-ketosteroid 5alpha-oxidoreductase activity in rat diencephalon.
1977
1977
The role of phospholipids in the activity of delta4-3-ketosteroid 5alpha-oxidoreductase of the rat ventral prostate.
The involvement of phospholipids in the activity of 5alpha-reductase from nuclear and microsomal fractions of rat prostate was… 
1976
1976
The metabolism of testosterone in the brain: the occurrence of delta4-3-ketosteroid 5 alpha-oxidoreductase and 3alpha-hydroxysteroid dehydrogenase and the effects of central acting drugs on these…
1975
1975
Letter: Irreversible inhibition of delta-5-3-ketosteroid isomerase by 5,10-secosteroids.
1963
1963
[COLORIMETRIC DETERMINATION OF DELTA-1,4-3-KETOSTEROID AND DELTA-4-3-KETOSTEROID HORMONES AND THEIR PREPARATIONS BY MEANS OF ISONICOTINIC ACID HYDRAZIDE].
1950
1950
Bromination of Certain Ketosteroids and a Partial Synthesis of Œstradiol, Œstrone and Equilenin
IT has been claimed repeatedly in the literature1 that the conversion of a Δ4-3-ketosteroid (I), for example, testosterone, into… 
1949
1949
On the Metabolism of $delta$$sup 4$,$sup 5--$ Cholestenone
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