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chalepin

National Institutes of Health

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Furocoumarins

Papers overview

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2020
2020
ENHANCEMENT OF ANTI-HEPATITIS C VIRUS ACTIVITY BY THE COMBINATION OF CHALEPIN FROM RUTA ANGUSTIFOLIA AND CURRENT ANTIVIRAL DRUGS: Tutik Sri Wahyuni1,2, Adita Ayu Permanasari2; Aty Widyawaruyanti1…
Hepatitis C virus (HCV) infection is a serious disease, which chronically infects 71 million people worldwide. Currently oral… 
2018
2018
Cytotoxic investigation of crude extracts and isolated compounds from Ruta angustifolia Pers. leaves and effects of chalepin on the expression of selected cancer-related proteins in human lung…
Plants have been a major source of inspiration in developing novel drug compounds for the treatment of various diseases that… 
2012
2012
P 28: Some contributions to the evaluation of ethnomedical antidiabetic claims of African medicinal plants
2007
2007
Computational Study of Glyceraldehyde-3-phosphate Dehydrogenase of Entamoeba histolytica: Implications for Structure-Based Drug Design
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of the pathogenic protozoa Entamoeba histolytica (Eh) is a major… 
2004
2004
New 3-piperonylcoumarins as inhibitors of glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH) from Trypanosoma cruzi.
2003
2003
3D QSAR studies on binding affinities of coumarin natural products for glycosomal GAPDH of Trypanosoma cruzi
Drug design strategies based on Comparative Molecular Field Analysis (CoMFA) have been used to predict the activity of new… 
1983
1983
Mutation of Chinese Hamster V79 cells and transformation and mutation of mouse fibroblast C3H/10T1/2 clone 8 cells by aflatoxin B1 and four other furocoumarins isolated from two Nigerian medicinal…
Mutation by aflatoxin B1 (AFB1), imperatorin, marmesin, chalepin, and 8-methoxypsoralen (MOP), with and without black light (BL… 
1983
1983
Inhibition of mitochondrial respiration by chalepin, a naturally occurring furocoumarin.
1981
1981
Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.
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