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Chalcones and chalcone epoxides are important synthetic intermediates in organic and medicinal chemistry. Chalcones possess a… Expand Objectives Study of the mechanisms involved in cancer progression suggests that cyclooxygenase enzymes play an important role in… Expand Safe and effective chemotherapeutic agents for the treatment of pancreatic cancer remain elusive. We found that chalcone epoxides… Expand The stilbenoid constituents of Combretum caffrum possess pronounced antineoplastic and antimitotic activities. The most potent… Expand The synthesis of 1-(2-hydroxyethyl)-3,5-diphenyl-1H-pyrazole (II) and its 4-bromo derivative (III) starting from chalcone epoxide… Expand The influence of metyrapone, chalcone epoxide, benzil and clotrimazole on the activity of microsomal epoxide hydrolase towards… Expand Membrane-bound and soluble epoxide hydrolase activities in the mononuclear cell fraction from human blood have been characterized… Expand