centriole assembly

Centriole duplication occurs once per cell cycle in order to maintain control of centrosome number and ensure genome integrity… Expand

Centrioles are cylindrical structures that are usually composed of nine triplets of microtubules (MTs) organized around a… Expand

Centrioles organise centrosomes and template cilia and flagella. Several centriole and centrosome proteins have been linked to… Expand

The centriole is an evolutionarily conserved macromolecular structure that is crucial for the formation of flagella, cilia and… Expand

Multiciliate cells function prominently in the respiratory system, brain ependyma and female reproductive tract to produce… Expand

Centrioles form the core of the centrosome in animal cells and function as basal bodies that nucleate and anchor cilia at the… Expand

We show that overexpression of Polo-like kinase 4 (Plk4) in human cells induces centrosome amplification through the simultaneous… Expand

Ciliated epithelial cells have the unique ability to generate hundreds of centrioles during differentiation. We used centrosomal… Expand

Centrioles are necessary for flagella and cilia formation, cytokinesis, cell-cycle control and centrosome organization/spindle… Expand

Centrioles organize pericentriolar material to form centrosomes and also template the formation of cilia. Despite the importance… Expand