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centriole assembly

A cellular process that results in the assembly of one or more centrioles. [GOC:dos, PMID:24075808]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
0519722017

Papers overview

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2015
2015
Binding of STIL to Plk4 activates kinase activity to promote centriole assembly
Centriole duplication occurs once per cell cycle in order to maintain control of centrosome number and ensure genome integrity… (More)
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2014
2014
Multicilin drives centriole biogenesis via E2f proteins.
Multiciliate cells employ hundreds of motile cilia to produce fluid flow, which they nucleate and extend by first assembling… (More)
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Highly Cited
2013
Highly Cited
2013
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly.
Centrioles are cylindrical structures that are usually composed of nine triplets of microtubules (MTs) organized around a… (More)
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Highly Cited
2012
Highly Cited
2012
Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation
Multiciliate cells function prominently in the respiratory system, brain ependyma and female reproductive tract to produce… (More)
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2010
2010
Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly
Centrioles form the core of the centrosome in animal cells and function as basal bodies that nucleate and anchor cilia at the… (More)
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2010
2010
Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication
Centrosome duplication occurs once every cell cycle in a strictly controlled manner. Polo-like kinase 4 (PLK4) is a key regulator… (More)
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2010
2010
Mps1 Phosphorylation Sites Regulate the Function of Centrin 2 in Centriole Assembly
The nondegradable Mps1(Δ12/13) protein drives centriole overproduction, suggesting that Mps1 phosphorylates a subset of… (More)
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Highly Cited
2007
Highly Cited
2007
DSAS-6 Organizes a Tube-like Centriole Precursor, and Its Absence Suggests Modularity in Centriole Assembly
Centrioles are microtubule-based cylindrical structures that exhibit 9-fold symmetry and facilitate the organization of… (More)
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Highly Cited
2006
Highly Cited
2006
Centriole assembly in Caenorhabditis elegans.
Centrioles are necessary for flagella and cilia formation, cytokinesis, cell-cycle control and centrosome organization/spindle… (More)
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Highly Cited
2001
Highly Cited
2001
Kinetics and regulation of de novo centriole assembly Implications for the mechanism of centriole duplication
BACKGROUND Centriole duplication is a key step in the cell cycle whose mechanism is completely unknown. Why new centrioles always… (More)
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