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cellulose synthase (UDP-forming) activity

Known as: 1,4-beta-glucan synthase activity, beta-1,4-glucosyltransferase activity, UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity 
Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1). [EC:2.4.1.12]
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Studies of the paradoxical effect of caspofungin at high drug concentrations.
Highly Cited
1996
Highly Cited
1996
In Vitro Activity of 1,3-β-D-Glucan Synthase Requires the GTP-binding Protein Rho1*
In the yeast Saccharomyces cerevisiae, the family of RHO genes are implicated in the control of morphogenetic events although the… 
Highly Cited
1996
Highly Cited
1996
Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies
The pneumocandins are potent antifungal agents of the echinocandin class which are under development for use as broad-spectrum… 
Highly Cited
1996
Highly Cited
1996
Rho 1 GTPase activates the (1–3)beta‐D‐glucan synthase and is involved in Schizosaccharomyces pombe morphogenesis.
The Schizosaccharomyces pombe Cdc42 and Rho1 GTPases were tested for their ability to complement the cwg2‐1 mutant phenotype of a… 
Highly Cited
1994
Highly Cited
1994
Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase
The lipopeptide antifungal agents, echinocandins, papulacandins, and pneumocandins, kill Candida albicans by inhibiting glucan… 
Highly Cited
1994
Highly Cited
1994
Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis
k9 killer toxin from Hansenula mrakii was used to select a number of resistant mutants from Saccharomyces cerevisiae. Preliminary… 
Highly Cited
1994
Highly Cited
1994
Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-1 killer toxin, which inhibits beta-glucan synthesis
A gene whose overexpression can endow Saccharomyces cerevisiae cells with resistance to HM-1 killer toxin was cloned from an S… 
Highly Cited
1993
Highly Cited
1993
The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta‐glucan synthesis.
The product of the Schizosaccharomyces pombe cwg2+ gene is involved in the biosynthesis of beta‐D‐glucan. When grown at the non… 
Highly Cited
1991
Highly Cited
1991
Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitro.
The KRE6 gene product is required for synthesis of the major beta-glucans of the yeast cell wall, as mutations in this gene… 
Highly Cited
1988
Highly Cited
1988
Cilofungin (LY121019) inhibits Candida albicans (1-3)-beta-D-glucan synthase activity
Cilofungin (LY121019) inhibited Candida albicans growth and activity of (1-3)-beta-glucan synthase, for which it was a… 
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