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cellular response to DNA damage stimulus

Known as: cellular DNA damage response, DNA damage response, response to genotoxic stress 
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a… 
National Institutes of Health

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histone H3-K56 acetylation in response to DNA damagehistone H4 acetylation involved in response to DNA damage stimulus
regulation of response to DNA damage stimulus

Papers overview

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Review
2015
Review
2015
The Ku heterodimer: function in DNA repair and beyond.
Highly Cited
2012
Highly Cited
2012
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway
The DNA damage response (DDR) cascade and ROS (reactive oxygen species) signaling are both involved in the induction of cell… 
Review
2012
Review
2012
Virus-mediated gene delivery for human gene therapy.
Review
2011
Review
2011
DNA damage response.
Structural changes to DNA severely affect its functions, such as replication and transcription, and play a major role in age… 
Highly Cited
2010
Highly Cited
2010
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Regulatory ubiquitylation is emerging as an important mechanism to protect genome integrity in cells exposed to DNA damage… 
Review
2010
Review
2010
Histone γH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers
Tumor cells are often deficient in DNA damage response (DDR) pathways, and anticancer therapies are commonly based on genotoxic… 
Highly Cited
2008
Highly Cited
2008
Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions
The cellular DNA damage response (DDR) is initiated by the rapid recruitment of repair factors to the site of DNA damage to form… 
Highly Cited
2007
Highly Cited
2007
Dysfunctional telomeres activate an ATM‐ATR‐dependent DNA damage response to suppress tumorigenesis
The POT1 (protection of telomeres) protein binds the single‐stranded G‐rich overhang and is essential for both telomere end… 
Highly Cited
2002
Highly Cited
2002
Combined Functional Genomic Maps of the C. elegans DNA Damage Response
Many human cancers originate from defects in the DNA damage response (DDR). Although much is known about this process, it is… 
Highly Cited
1998
Highly Cited
1998
The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response
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