ceftolozane

Known as: (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 
 
National Institutes of Health

Papers overview

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2017
2017
OBJECTIVES The increase in infections caused by drug-resistant ESBL-producing Enterobacteriaceae (ESBL-ENT) is a global concern… (More)
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2017
2017
BACKGROUND/AIMS To determine ceftolozane/tazobactam transmembrane clearances (CLTM) in continuous hemofiltration (CHF) and… (More)
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2014
2014
Ceftolozane/tazobactam is under clinical development for treatment of complicated intra-abdominal infections (IAI), complicated… (More)
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2014
2014
OBJECTIVES To evaluate the in vitro activity of ceftolozane/tazobactam and comparator agents tested against contemporary Gram… (More)
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2014
2014
Ceftolozane is a novel cephalosporin with activity against drug-resistant pathogens, including Pseudomonas aeruginosa and… (More)
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Review
2013
Review
2013
Ceftolozane is a novel cephalosporin currently being developed with the β-lactamase inhibitor tazobactam for the treatment of… (More)
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2013
2013
We recently investigated the pharmacokinetics-pharmacodynamics (PK-PD) of tazobactam in combination with ceftolozane against an… (More)
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2013
2013
Despite β-lactamase inhibitors being available for clinical use for nearly 30 years, a paucity of data exists describing the… (More)
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2013
2013
Ceftolozane is a new cephalosporin with potent activity against Pseudomonas aeruginosa and Enterobacteriaceae. A neutropenic… (More)
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2012
2012
OBJECTIVES Appropriate antibiotic exposure at the site of infection is important for clinically effective therapy. This study… (More)
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