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cefditoren pivoxil
Known as:
7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(2-(4-methylthiazol-5-yl)ethenyl)cephem-4-carboxylic acid pivaloyloxymethyl ester
, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((1Z)-2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl Ester,(6R,7R)-
, cefditoren pivoxil [Chemical/Ingredient]
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A semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil…
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National Institutes of Health
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Related topics
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16 relations
Broader (2)
Anti-Bacterial Agents
cefditoren
Bacterial Infections
Bronchitis
Cephalosporins
Drug Allergy
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Narrower (1)
ME 1207
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria
Evelyne Lacasse
,
É. Brouillette
,
Audrey Larose
,
T. Parr
,
A. Rubio
,
F. Malouin
Antimicrobial Agents and Chemotherapy
2019
Corpus ID: 73440325
Tebipenem (SPR859) is the microbiologically active form of SPR994 (tebipenem-pivoxil), an orally available carbapenem with…
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2009
2009
Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2.
L. Todesco
,
M. Bodmer
,
Karin Vonwil
,
D. Häussinger
,
S. Krähenbühl
Chemico-Biological Interactions
2009
Corpus ID: 1779400
2008
2008
High Protein Binding and Cidal Activity against Penicillin-Resistant S. pneumoniae: A Cefditoren In Vitro Pharmacodynamic Simulation
D. Sevillano
,
L. Aguilar
,
+7 authors
J. Prieto
PLoS ONE
2008
Corpus ID: 392246
Background Although protein binding is a reversible phenomenon, it is assumed that antibacterial activity is exclusively exerted…
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2007
2007
Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for Its High Antimicrobial Activity
M. Yamada
,
Takashi Watanabe
,
+4 authors
F. Ohsawa
Antimicrobial Agents and Chemotherapy
2007
Corpus ID: 25596933
ABSTRACT Cefditoren is the active form of cefditoren pivoxil, an oral cephalosporin antibiotic used for the treatment of…
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2007
2007
Pharmacokinetic/pharmacodynamic serum and urine profile of cefditoren following single-dose and multiple twice- and thrice-daily regimens in healthy volunteers: a phase I study.
B. Sádaba
,
Azanza
,
+4 authors
M. Gimeno
Revista Espanola de Quimioterapia
2007
Corpus ID: 25741402
The objectives of this randomized, double-blind study were to evaluate the pharmacokinetics, and the pharmacodynamic and…
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2007
2007
Urine Bactericidal Activity against Escherichia coli Isolates Exhibiting Different Resistance Phenotypes/Genotypes in an In Vitro Pharmacodynamic Model Simulating Urine Concentrations Obtained after…
D. Sevillano
,
L. Aguilar
,
+7 authors
J. Prieto
Antimicrobial Agents and Chemotherapy
2007
Corpus ID: 31730161
ABSTRACT Activity of simulated cefditoren urinary concentrations was determined against seven Escherichia coli isolates…
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2000
2000
Antimicrobial activity and in vitro susceptibility test development for cefditoren against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus species.
David M. Johnson
,
D. Biedenbach
,
M. Beach
,
M. Pfaller
,
Ronald N. Jones
Diagnostic microbiology and infectious disease
2000
Corpus ID: 23619825
1999
1999
Comparison of Crystallinity of Cefditoren Pivoxil Determined by X-Ray, Differential Scanning Calorimetry and Microcalorimetry
M. Ohta
,
Y. Tozuka
,
T. Oguchi
,
Keiji. Yamamoto
1999
Corpus ID: 39893580
The heat of crystallization and heat of solution of cefditoren pivoxil of different crystallinities were determined by…
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1997
1997
Phase I clinical trial of cefditoren pivoxil (ME 1207): pharmacokinetics in healthy volunteers.
J. Li
,
F. Hou
,
H. Lu
,
T. Li
,
H. Li
Drugs under experimental and clinical research
1997
Corpus ID: 41186409
Pharmacokinetics of ME1207 were evaluated in 5 groups of healthy adult male volunteers given single preprandial administration of…
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1993
1993
[Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients].
R. Fujii
,
S. Chiba
,
+7 authors
Y. Satoh
The Japanese Journal of Antibiotics
1993
Corpus ID: 478871
Carnitine metabolism was studied in 16 pediatric patients with various infections under the treatment with cefditoren pivoxil…
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