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  • Influence
Maternal immune activation and abnormal brain development across CNS disorders
TLDR
The emerging evidence that mIA is a shared environmental risk factor across CNS disorders that varies as a function of interactions between genetic and additional environmental factors is critically reviewed. Expand
Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia
TLDR
Lactic acidosis during current use of oral antidiabetes drugs was very rare and was associated with concurrent comorbidity. Expand
Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer
TLDR
A decreased risk of breast cancer was observed in female patients with type 2 diabetes using metformin on a long-term basis, and neither short-term met formin use nor use of sulfonylureas or other antidiabetes drugs was associated with a materially altered risk for breast cancer. Expand
Metformin, Other Antidiabetic Drugs, and Risk of Alzheimer's Disease: A Population‐Based Case–Control Study
TLDR
To explore the risk of developing Alzheimer's disease in individuals with diabetes mellitus treated with metformin or other antidiabetic drugs, a large number of patients treated with these drugs have been diagnosed with AD. Expand
Use of metformin and the risk of ovarian cancer: a case-control analysis.
TLDR
In this large epidemiological study long-term use of metformin, but not of sulfonylureas, was associated with a tendency towards a decreased risk of ovarian cancer. Expand
Use of thiazolidinediones and fracture risk.
TLDR
This nested case-control analysis provides further evidence of a possible association between long-term use of thiazolidinediones and fractures, particularly of the hip and wrist, in patients with diabetes mellitus. Expand
Drug - related emergency department visits by elderly patients presenting with non-specific complaints
TLDR
Elderly patients with non-specific complaints need to be screened systematically for drug-related problems, and polypharmacy and certain drug classes were associated with DRPs. Expand
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
TLDR
Findings support the use of a 5-day glucocorticoid treatment in acute exacerbations of COPD, with no difference between groups in time to death, the combined end point of exacerbation, death, or both and recovery of lung function. Expand
Metformin and the risk of endometrial cancer: a case-control analysis.
TLDR
Use of metformin and other antidiabetic drugs were not associated with an altered risk of endometrial cancer. Expand
Use of Metformin Is Not Associated with a Decreased Risk of Colorectal Cancer: A Case–Control Analysis
TLDR
Use of metformin was linked to an increased risk of colorectal cancer in men and use of sulfonylureas or insulin was not associated with an altered risk of colon cancer. Expand
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