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caudatin

National Institutes of Health

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GlycosidesSteroids

Papers overview

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2015
2015
Caudatin Inhibits Human Glioma Cells Growth Through Triggering DNA Damage-Mediated Cell Cycle Arrest
Caudatin, one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne, exhibits… 
2015
2015
Pharmacokinetics and Tissue Distribution Study of Caudatin in Normal and Diethylnitrosamine-Induced Hepatocellular Carcinoma Model Rats
Caudatin is a potential antitumor agent isolated from the traditional Chinese medicine “baishouwu”, which was the root tuber of… 
2015
2015
Design, Synthesis and Biological Evaluation of Caudatin and its Ester Derivatives as Novel Antitumor Agents
A series of caudatin ester derivatives were synthesized and tested for their activities against human lung cancer A549, human… 
2015
2015
Design, synthesis and biological evaluation of caudatin analogs as potent hepatitis B virus inhibitors.
Thirty-nine caudatin analogs were designed and synthesized. Their anti-hepatitis B virus (HBV) activities were evaluated in vitro… 
2015
2015
Determination of Caudatin in Rat Plasma by UPLC-MS/MS: Application to a Preclinical Pharmacokinetic Study
In this study, a simple, sensitive, and robust analytical method based on ultra-performance liquid chromatography tandem mass… 
2013
2013
Caudatin inhibits human hepatoma cell growth and metastasis through modulation of the Wnt/β-catenin pathway.
In the present study, we investigated the antitumor activity of caudatin in the human hepatoma cell line SMMC‑7721 by analysis of… 
2010
2010
Oral Pharmacokinetics of Caudatin in Rats
AIM: To study the pharmacokinetics after oral administration of caudatin in rats. METHODS: Blood samples of rats were collected… 
2009
2009
Structural characterization of pregnane glycosides from Cynanchum auriculatum by liquid chromatography on a hybrid ion trap time-of-flight mass spectrometer.
A method coupling high-performance liquid chromatography with hybrid ion trap time-of-flight mass spectrometry (TOFMS) using an… 
2008
2008
Study on Determination of Caudatin in Rat Plasma by LC-MS-MS
OBJECTIVE To develop a sensitive and specific LC-MS-MS method for the determination of caudatin in rat plasma.METHODS The analyte… 
2003
2003
Acylated-oxypregnane glycosides from the roots of Araujia sericifera.
Twenty-three new acylated-oxypregnane glycosides were obtained from the roots of Araujia sericifera. (Asclepiadaceae). These… 
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