cathepsin B activity

OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2018
0102019672018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Inhalation of silica crystals causes inflammation in the alveolar space. Prolonged exposure to silica can lead to the development… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Atherosclerotic plaque rupture, the most important cause of acute cardiovascular incidents, has been strongly… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1999
1999
Lysosomal cathepsin B has been implicated in parasitic, inflammatory and neoplastic diseases. Most of these pathologies suggest a… (More)
Is this relevant?
1997
1997
Within the lysosomal cysteine protease family, cathepsin B is unique due to its ability to act both as an endopeptidase and a… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS Bile salt-induced apoptosis is mediated by a trypsin-like nuclear protease. The aims of this study were to… (More)
Is this relevant?
1995
1995
Cathepsin B (CB) activity was measured in aqueous extracts of frozen autopsy specimens of centrum semiovale from three MS… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Gelatinase A (MMP-2) and cathepsin B are proteinases which have been proposed to participate in human tumor invasion and… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Our laboratory has previously demonstrated that increased malignancy of several histological types of human and animal tumours is… (More)
Is this relevant?
1982
1982
In solid s.c. tumors of a variant of the murine B16 melanoma with high metastatic potential (B16F10), there was a 2- to 7-fold… (More)
Is this relevant?
Highly Cited
1981
Highly Cited
1981
Although lysosomal enzymes are implicated in the processes of tumor invasion and metastasis, their cellular origin within the… (More)
Is this relevant?