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cathepsin B activity

OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in… Expand
National Institutes of Health

Papers overview

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2018
2018
Inhibition of cathepsin B activity prevents deterioration in the quality of in vitro aged porcine oocytes.
The activity of cathepsin B, a member of the lysosomal protease family, directly correlates with oocyte quality and subsequent… Expand
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2017
2017
One session of exercise regulates cathepsin B activity in the livers of trained and untrained rats.
Physical exercise causes adaptive changes, mainly in muscles, but it also influences other organs, including liver. Most changes… Expand
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Highly Cited
2013
Highly Cited
2013
OxLDL-induced IL-1beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation
ObjectiveIL-1β is a master switch of inflammation and plays an important role in the pathogenesis of vascular disease. During… Expand
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2009
2009
Regulation of cathepsin B activity by 2A2 monoclonal antibody.
Cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity. The former is… Expand
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Highly Cited
2005
Highly Cited
2005
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells.
The lysosomal protease cathepsin B has been implicated in a variety of pathologies including pancreatitis, tumor angiogenesis… Expand
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1996
1996
Cathepsin B activity in normal human osteoblast-like cells and human osteoblastic osteosarcoma cells (MG-63): regulation by interleukin-1 beta and parathyroid hormone.
Cathepsin B activity and its regulation by interleukin 1 beta (IL-1 beta) and parathyroid hormone (PTH) was investigated in… Expand
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1995
1995
Assessment of cathepsin L activity by use of the inhibitor CA-074 compared to cathepsin B activity in human lung tumor tissue.
In a series of pairs of lung tumor tissue and non-tumor lung parenchyma from 50 patients, the activity of cathepsin L was… Expand
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1990
1990
Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors.
Our laboratories have previously demonstrated that the malignancy of human and animal tumors is associated with increases in… Expand
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1979
1979
Cathepsin B activity in stimulated mouse peritoneal macrophages.
The activity of cathepsin B was assayed in murine resident peritoneal macrophages, and after stimulation of the cells in vivo and… Expand
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1967
1967
Haptoglobin acting as a Natural Inhibitor of Cathepsin B Activity
OBSERVATIONS in this laboratory on various homogenates and on tumour ascites fluid1,2 have suggested that a component in blood… Expand
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