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Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers.
AIMS Persons with high intake of polyunsaturated fatty acids (PUFAs) have lower cardiovascular morbidity and mortality. The protective effect of PUFAs is mediated by multiple mechanisms, includingExpand
Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study.
Although recent epidemiological studies found a positive correlation between dietary vitamin C intake and bone mineral density, data on plasma levels of vitamin C or other antioxidants inExpand
Validation of the Five‐Item Geriatric Depression Scale in Elderly Subjects in Three Different Settings
OBJECTIVES: To test the effectiveness of a five‐item version of the Geriatric Depression Scale (GDS) for the screening of depression in community‐dwelling older subjects, hospitalized older patients,Expand
Uric acid and inflammatory markers.
AIMS The role of uric acid (UA) in the process of atherosclerosis and atherotrombosis is controversial. Epidemiological studies have recently shown that UA may be a risk factor for cardiovascularExpand
Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle.
A role for oxidative damage in normal aging is supported by studies in experimental animals, but there is limited evidence in man. We examined markers of oxidative damage to DNA, lipids, and proteinsExpand
Proton magnetic resonance spectroscopy can differentiate Alzheimer's disease from normal aging
In order to evaluate the pattern of proton magnetic resonance spectroscopy (1H-MRS) in the gray and white matter of patients with Alzheimer's disease (AD) and healthy controls, a cross-sectionalExpand
Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.
CONTEXT A large body of experimental evidence suggests that in Alzheimer disease (AD) pathogenesis an important role is played by oxidative stress, but there is still a lack of data on in vivoExpand
Age and sex influence on oxidative damage and functional status in human skeletal muscle
A reduction in muscle mass, with consequent decrease in strength and resistance, is commonly observed with advancing age. In this study we measured markers of oxidative damage to DNA, lipids andExpand
White blood cell count and mortality in the Baltimore Longitudinal Study of Aging.
OBJECTIVES We investigated the secular trend in white blood cell (WBC) count and the relationship between WBC count and mortality between 1958 and 2002. BACKGROUND The WBC count is a clinicalExpand
Antioxidant Profile and Early Outcome in Stroke Patients
Background and Purpose Experimental studies provide evidence of an association between ischemic stroke and increased oxidative stress, but data in humans are still limited and controversial. TheExpand