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carboxyimamidate

Known as: Carbethimer, POLIMA, Carbetimer 
Carbetimer (carboxyimamidate) is a low molecular weight derivatized copolymer of ethylene and maleic anhydride. It has demonstrated antitumor… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsImmunologic AdjuvantsPolymerspermease

Narrower (1)

NED 137

Papers overview

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2004
2004
Activity of Carbetimer in a human tumor cloning system
SummaryThe antitumor activity of Carbetimer was tested against 171 patient's tumors in a human tumor cloning system. Sixty-seven… 
1989
1989
Phase I clinical trial with carbetimer.
1989
1989
Short-term effects of Carbetimer on calcium and bone metabolism in man.
1988
1988
Phase I trial of the polyelectrolyte carbetimer administered i.v. once every four weeks
SummaryCarbetimer, a new synthetic low molecular weight polyelectrolyte with a novel structure displayed antitumor activiy in a… 
1988
1988
Phase I clinical trial of carbetimer.
Carbetimer (carbethimer, N-137, NED-137, carboxyimamidate) is a low molecular weight polyelectrolyte with antitumor activity in a… 
1987
1987
The combination of polima cms and cytoplasmic triazine resistance in Brassica napus
SummaryProtoplast fusion was used to combine cytoplasmic triazine resistance (ctr) and Polima type cytoplasmic male sterility… 
1986
1986
Mechanism of action of a new antitumor agent, carbetimer.
Carbetimer, an intermediate molecular-weight-derivatized copolymer of maleic anhydride and ethylene, has been shown to possess… 
1986
1986
Growth of carcinoma of the esophagus and gastroesophageal junction in a human tumor cloning assay.
We have received and attempted to culture 23 specimens from 23 patients with squamous cell carcinoma of the esophagus and 15… 
1986
1986
Phase I trial with carbetimer given on a 5 day schedule
1982
1982
Carboxyimamidate, a low-molecular-weight polyelectrolyte with antitumor properties and low toxicity.
A new polyelectrolyte was synthesized and evaluated for antitumor activity. The product is a derivative of ethylene/maleic… 
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