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carboprostacyclin
Known as:
6,9-methano-PGI2
, (5E)-6a-carba-prostaglandin I2
, Pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-2(1H)-pentalenylidene)-, (3aS-(2E,3aalpha,4alpha(1E,3R*),5beta,6aalpha))-
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Epoprostenol
Platelet Aggregation Inhibitors
analogs & derivatives
Narrower (1)
carboprostacyclin, monosodium salt
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.
James Chadwick
,
A. Mercer
,
B. Park
,
R. Cosstick
,
P. O’Neill
Bioorganic & Medicinal Chemistry
2009
Corpus ID: 19467014
1997
1997
Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs.
D. Abran
,
Daya R. Varma
,
Sylvain Chemtob
American Journal of Physiology
1997
Corpus ID: 3025940
This study was conducted to determine if high perinatal prostaglandin (PG) and thromboxane (TxA2) levels modified their choroidal…
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1996
1996
Prostaglandin F2 alpha stimulates hypertrophic growth of cultured neonatal rat ventricular myocytes.
J. Adams
,
D. S. Migita
,
+7 authors
S. Henderson
Journal of Biological Chemistry
1996
Corpus ID: 22215353
Prostaglandin F2 alpha (PGF2 alpha) stimulates protein synthesis of skeletal and smooth muscle cells in culture and is elevated…
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1995
1995
Roles of Prostaglandins D2 and E2 in Interleukin‐1‐Induced Activation of Norepinephrine Turnover in the Brain and Peripheral Organs of Rats
A. Terao
,
H. Kitamura
,
A. Asano
,
Mari Kobayashi
,
Masayuki Saito
Journal of Neurochemistry
1995
Corpus ID: 34121500
Abstract: Possible roles of prostaglandins (PGs) in interleukin‐1 (IL‐1)‐induced activation of noradrenergic neurons were…
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1994
1994
Reduced responses of retinal vessels of the newborn pig to prostaglandins but not to thromboxane.
D. Abran
,
D. Varma
,
D. Y. Li
,
S. Chemtob
Canadian Journal of Physiology and Pharmacology
1994
Corpus ID: 40211066
The upper blood pressure limit of retinal blood flow autoregulation is lower in the newborn than in the adult; this suggests an…
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1990
1990
Identification of a prostacyclin receptor coupled to the adenylate cyclase system via a stimulatory GTP-binding protein in mouse mastocytoma P-815 cells.
H. Hashimoto
,
M. Negishi
,
A. Ichikawa
Prostaglandins
1990
Corpus ID: 23384242
1989
1989
Leukotriene formation by human polymorphonuclear leukocytes from endogenous arachidonate. Physiological triggers and modulation by prostanoids.
M. Haurand
,
L. Flohé
Biochemical Pharmacology
1989
Corpus ID: 29207394
1985
1985
Desensitization of prostacyclin responsiveness in a neuronal hybrid cell line: selective loss of high affinity receptors
P. J. Leigh
,
J. Macdermot
British Journal of Pharmacology
1985
Corpus ID: 33174785
1 The binding of [3H]‐iloprost (ZK36374) to NCB‐20 membranes revealed a single population of high affinity receptors (KD = 9.55…
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Highly Cited
1984
Highly Cited
1984
Platelet Involvement in the Activated Coagulation Time of Heparinized Blood
M. Moorehead
,
J. Westengard
,
B. Bull
Anesthesia and Analgesia
1984
Corpus ID: 36133672
The activated coagulation time (ACT), commonly used during cardiopulmonary bypass (CPB), is assumed to measure only differences…
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1982
1982
Dissociation of Antiplatelet Effects from Myocardial Cytoprotective Activity During Acute Myocardial Ischemia in Cats by a New Carbacyclin Derivative (ZK 36 375)
K. Schrör
,
H. Darius
,
R. Ohlendorf
,
R. Matzky
,
W. Klaus
Journal of Cardiovascular Pharmacology
1982
Corpus ID: 32990522
We studied the potential therapeutic value of the chemically stable carbacyclin analogue ZK 36 375 during acute myocardial…
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