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capuramycin

Known as: beta-D-Allofuranuronamide, 1-deoxy-5-O-(4-deoxy-N-(hexahydro-2-oxo-1H-azepin-3-yl)-alpha-L-erythro-hex-4-enopyranuronamidosyl)-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-O-methyl-, (S)- 
 
National Institutes of Health

Papers overview

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2015
2015
Capuramycin (1) and its analogs are strong translocase I (MurX/MraY) inhibitors. In our structure–activity relationship studies… Expand
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2015
2015
Background: Several nucleoside antibiotics contain a uridine-5′-carboxamide core of unclear origin. Results: The A-102395… Expand
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2010
2010
OBJECTIVES To determine antibacterial activity of capuramycin analogues SQ997, SQ922, SQ641 and RKS2244 against several non… Expand
Highly Cited
2009
Highly Cited
2009
ABSTRACT New delivery vehicles and routes of delivery were developed for the capuramycin analogue SQ641. While this compound has… Expand
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2009
2009
A concise total synthesis of capuramycin (1), a promising preclinical TB drug lead, is achieved by high-yield formations of the… Expand
Highly Cited
2007
Highly Cited
2007
ABSTRACT Translocase I inhibitor compounds derived from capuramycin demonstrated rapid bactericidal activity against several… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES The antimycobacterial activities of RS-112997, RS-124922 and RS-118641, three capuramycin analogues that inhibit… Expand
2003
2003
Acylated derivatives of capuramycin and A-500359A were synthesized and tested for antimycobacterial activity. Compound 20 having… Expand
2003
2003
Capuramycin analogues with a variety of substituents in place of the azepan-2-one moiety were synthesized from A-500359E and were… Expand
Highly Cited
1986
Highly Cited
1986
A new antibiotic capuramycin was isolated from the culture filtrate of Streptomyces griseus 446-S3 by adsorption and partition… Expand
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