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cambinol

 
National Institutes of Health

Papers overview

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2015
2015
Ceramide is a bioactive lipid that plays an important role in stress responses leading to apoptosis, cell growth arrest and… Expand
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Highly Cited
2014
Highly Cited
2014
Sirtuins are a family of NAD+-dependent protein deacetylases that play critical roles in epigenetic regulation, stress responses… Expand
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2013
2013
Sirtuins (SIRT1-7) are NAD(+)-dependent histone deacetylases (HDACs) that play an important role in the control of metabolism and… Expand
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Highly Cited
2013
Highly Cited
2013
Sirtuins (SIRT1-7) are a highly conserved family of NAD+-dependent enzymes that control the activity of histone and nonhistone… Expand
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Highly Cited
2011
Highly Cited
2011
The N-Myc oncoprotein is a critical factor in neuroblastoma tumorigenesis which requires additional mechanisms converting a low… Expand
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Highly Cited
2011
Highly Cited
2011
Aberrant histone deacetylase (HDAC) activity is frequent in human leukemias. However, while classical, NAD+-independent HDACs are… Expand
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2011
2011
The human deacetylase SIRT2 is believed to promote neurodegeneration with recent studies demonstrating that a reduction in the… Expand
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Highly Cited
2009
Highly Cited
2009
The tenovins and cambinol are two classes of sirtuin inhibitor that exhibit antitumor activity in preclinical models. This report… Expand
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2009
2009
OBJECTIVE Megakaryocytic cells (Mks) undergo endomitosis and become polyploid. Mk ploidy correlates with platelet production. We… Expand
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Highly Cited
2006
Highly Cited
2006
SIRT1 and other NAD-dependent deacetylases have been implicated in control of cellular responses to stress and in tumorigenesis… Expand
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