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cambinol

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Ceramide is a bioactive lipid that plays an important role in stress responses leading to apoptosis, cell growth arrest and… Expand
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Highly Cited
2014
Highly Cited
2014
Sirtuins are a family of NAD+-dependent protein deacetylases that play critical roles in epigenetic regulation, stress responses… Expand
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Highly Cited
2013
Highly Cited
2013
Sirtuins (SIRT1-7) are NAD(+)-dependent histone deacetylases (HDACs) that play an important role in the control of metabolism and… Expand
Review
2013
Review
2013
  • C. Gerhauser
  • Topics in current chemistry
  • 2013
  • Corpus ID: 1010163
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in DNA… Expand
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Review
2012
Review
2012
Sirtuins 1‐7 (SIRT1‐7) belong to the third class of deacetylase enzymes, which are dependent on NAD+ for activity. Sirtuins… Expand
Review
2011
Review
2011
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in DNA… Expand
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Highly Cited
2011
Highly Cited
2011
The N-Myc oncoprotein is a critical factor in neuroblastoma tumorigenesis which requires additional mechanisms converting a low… Expand
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Highly Cited
2011
Highly Cited
2011
Aberrant histone deacetylase (HDAC) activity is frequent in human leukemias. However, while classical, NAD+-independent HDACs are… Expand
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Highly Cited
2009
Highly Cited
2009
The tenovins and cambinol are two classes of sirtuin inhibitor that exhibit antitumor activity in preclinical models. This report… Expand
Highly Cited
2006
Highly Cited
2006
SIRT1 and other NAD-dependent deacetylases have been implicated in control of cellular responses to stress and in tumorigenesis… Expand
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