Skip to search formSkip to main contentSkip to account menu

calmodulin-dependent protein kinase III

Known as: Elongation Factor 2 Kinase [Chemical/Ingredient], eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III, Eukaryotic Elongation Factor 2 Kinase 
A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a… 
National Institutes of Health

Related topics

Related topics

9 relations
EEF2K geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (1)

EEF2K protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase
Triple negative breast cancer (TNBC) is an aggressive type of breast cancer characterized by the absence of defined molecular… 
Highly Cited
2014
Highly Cited
2014
Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling
ABSTRACT Eukaryotic elongation factor 2 kinase (eEF2K), an atypical calmodulin-dependent protein kinase, phosphorylates and… 
Highly Cited
2014
Highly Cited
2014
Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K
The tumor suppressors Pten and p53 are frequently lost in breast cancer, yet the consequences of their combined inactivation are… 
Review
2009
Review
2009
The role of protein synthesis in cell cycling and cancer
Highly Cited
2007
Highly Cited
2007
Characterization of the Role of Microtubule-Associated Protein 1B in Metabotropic Glutamate Receptor-Mediated Endocytosis of AMPA Receptors in Hippocampus
The mGluR-dependent endocytosis of AMPA receptors (AMPARs) in the CA1 region is protein synthesis dependent. However, why this… 
Highly Cited
2007
Highly Cited
2007
Lysophosphatidic Acid Facilitates Proliferation of Colon Cancer Cells via Induction of Krüppel-like Factor 5*
Among the multiple cellular effects mediated by lysophosphatidic acid (LPA), the effect on cell proliferation has extensively… 
Review
2004
Review
2004
Alpha-kinases: analysis of the family and comparison with conventional protein kinases.
Highly Cited
2002
Highly Cited
2002
Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.
Eukaryotic elongation factor 2 (eEF2) kinase, the enzyme that inactivates eEF2, is controlled by phosphorylation. Previous work… 
Highly Cited
2001
Highly Cited
2001
Novel Type of Signaling Molecules: Protein Kinases Covalently Linked with Ion Channels
Recently we identified a new class of protein kinases with a novel type of catalytic domain structurally and evolutionarily… 
Highly Cited
1997
Highly Cited
1997
Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.
The several hundred members of the eukaryotic protein kinase superfamily characterized to date share a similar catalytic domain… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)