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EEF2K protein, human

Known as: eEF-2K, eEF-2 kinase, human, eukaryotic elongation factor-2 kinase, human 
Eukaryotic elongation factor 2 kinase (725 aa, ~82 kDa) is encoded by the human EEF2K gene. This protein is involved in both the negative regulation… 
National Institutes of Health

Related topics

Related topics

14 relations
Calcium BindingCalcium-Binding ProteinsCytoplasmEEF2K gene

Broader (1)

calmodulin-dependent protein kinase III

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways
Previous studies have reported that eEF-2 kinase is associated with tumour cell sensitivity to certain therapies. In the present… 
2016
2016
Expression and localization of calmodulin-related proteins in brain, heart and kidney from spontaneously hypertensive rats.
2015
2015
eEF-2 Phosphorylation Down-Regulates P-Glycoprotein Over-Expression in Rat Brain Microvessel Endothelial Cells
Objective We investigated whether glutamate, NMDA receptors, and eukaryote elongation factor-2 kinase (eEF-2K)/eEF-2 regulate P… 
2014
2014
Surviving metabolic stress: of mice (squirrels) and men.
Understanding how cancer cells survive harsh environmental conditions may be fundamental to eradicating malignancies proven to be… 
2012
2012
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
The published version of Figure 4(B) was incorrect; the corrected Figure and caption are shown here. Figure 4 Changes in… 
2012
2012
F-Box Proteins Elongate Translation During Stress Recovery
An inhibitor of protein synthesis is activated by DNA damage and degraded during recovery. Protein synthesis is energetically… 
2012
2012
Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme's stability under stress conditions.
Highly Cited
2000
Highly Cited
2000
Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase.
1999
1999
An enzyme-linked immunosorbent assay for the association of the catalytic domain of diphthamide-specific ribosyltransferases to eukaryotic elongation factor-2.
The X-ray structure of the catalytic domain of Pseudomonas aeruginosa exotoxin A (PE24) has recently been solved to high… 
Highly Cited
1996
Highly Cited
1996
Cloning and Expression of cDNA Encoding Protein Synthesis Elongation Factor-2 Kinase*
A cDNA from rat skeletal muscle encoding calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase (eEF-2K) has been… 
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