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cactinomycin

Known as: ACTINOMYCIN C 
A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Cactinomycin binds to DNA by intercalating between… Expand
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
Peripheral motor nerve trauma severely compromises skeletal muscle contractile function. Satellite cells respond to denervation… Expand
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Highly Cited
1994
Highly Cited
1994
Effects of metallothionein (MT) synthesis inhibiting compounds (actinomycin D, cycloheximide), MT synthesis stimulating compounds… Expand
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Highly Cited
1990
Highly Cited
1990
Histones have been both radiolabeled and density-labeled with amino acids in vivo to determine the dynamics of histone-DNA and… Expand
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Highly Cited
1988
Highly Cited
1988
The effects of silicon deficiency on the activities of several enzymes involved in lipid and storage carbohydrate synthesis in… Expand
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Highly Cited
1987
Highly Cited
1987
Abstract RNA-dependent RNA polymerase (RDRP) activity was characterized in a cytoplasmic extract of Kunjin virus-infected… Expand
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Highly Cited
1979
Highly Cited
1979
A comparison of two rapid and inexpensive in vivo mammalian assays and the Ames Salmonella assay is presented for 61 agents… Expand
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Highly Cited
1974
Highly Cited
1974
Based on evidence that 50% of herpes simplex 1 DNA is transcribed in HEp-2 cells in the absence of protein synthesis we examined… Expand
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Highly Cited
1968
Highly Cited
1968
Abstract The biogenesis of vaccinia envelopes was examined by combined chemical and electron microscopic procedures. These… Expand
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Highly Cited
1968
Highly Cited
1968
In HeLa cells infected with type 1 poliovirus, the single-stranded viral RNA genome directs the synthesis of four capsid and ten… Expand
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Highly Cited
1966
Highly Cited
1966
Summary Puromycin and acetoxycycloheximide, antibiotics known to block selectively protein synthesis, also block the formation of… Expand
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