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cactinomycin

Known as: ACTINOMYCIN C 
A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Cactinomycin binds to DNA by intercalating between… 
National Institutes of Health

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Broader (5)

ActinomycinAnti-Bacterial AgentsAntibiotics, AntineoplasticDactinomycin
NCIt Antineoplastic Agent Terminologyactinomycin Xanalogs & derivatives

Papers overview

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Highly Cited
1977
Highly Cited
1977
HeLa cell poly(A)- mRNA codes for a subset of poly(A)+ mRNA-directed proteins with an actin as a major product.
Poly(A)+ and poly(A)- mRNA from HeLa cells were separated and translated in heterologous messenger-dependent protein synthesizing… 
1975
1975
Actinomycin D-deoxynucleotide complexes as models for the actinomycin D-DNA complex. The use of nuclear magnetic resonance to determine the stoichiometry and the geometry of the complexes.
The use of proton and carbon-13 magnetic resonance spectroscopy for the determination of the geometry and the stoichiometry of… 
1975
1975
Characterization of an in vitro persistent-state measles virus infection: establishment and virological characterization of the BGM/MV cell line
The parameters of a persistent-state measles virus infection in BGM/MV cells were examined. The BGM/MV cell line was established… 
1972
1972
Early estrogen action: stimulation of the metabolism of high molecular weight and ribosomal RNAs (estradiol-17 -RNA isolation-uterus-ribosomal RNA precursors-actinomycin D).
Samples of RNA, isolated from uteri of ovariectomized adult rats treated with estrogen, have been analyzed on sucrose gradients… 
1972
1972
Intracerebral antibiotics and androgenization of the neonatal female rat.
The possible mechanism of androgenization has been studied by intrahypothalamic application of actinomycin-D (0.17 µ g… 
Highly Cited
1971
Highly Cited
1971
Inhibitors acting on nucleic acid synthesis in an oncogenic RNA virus.
IN infection with an oncogenic RNA virus, synthesis of viral RNA seems to be catalysed by an RNA dependent DNA polymerase in the… 
1970
1970
Bacteriology of manganese nodules. IV. Induction of an MnO2-reductase system in a marine bacillus.
Bacillus 29, isolated from a ferromanganese nodule from the Atlantic Ocean, was shown to possess an MnO(2)-reductase system which… 
1969
1969
Role of interferon in replication of virulent and attenuated strains of measles virus.
Summary Small concentrations of actinomycin D increased the yields of both virulent and attenuated strains of measles virus in… 
Highly Cited
1965
Highly Cited
1965
Induction of chromosome breaks in cultured normal human leukocytes by potassium arsenite, hydroxyurea and related compounds.
Summary Hydroxyurea and N -hydroxyurethane at mm concentrations produced a high incidence of chromosome breaks along with other… 
1965
1965
An in vitro Action of Human Growth Hormone in the Presence of Actinomycin D
THE in vitro addition of growth hormone to isolated diaphragm from the hypophysectomized rat stimulates the uptake of glucose1–3… 
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