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buciclovir

Known as: BCV, 6H-Purin-6-one, 2-amino-9-(3,4-dihydroxybutyl)-1,9-dihydro-, 9-(3,4-dihydroxybutyl)guanine 
An acyclic guanosine analog with activity against herpes simplex virus (HSV). Buciclovir is phosphorylated to its triphosphate form by HSV thymidine… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Acyclovir
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
On A Nonlinear Generalization of Sparse Coding and Dictionary Learning
Existing dictionary learning algorithms are based on the assumption that the data are vectors in an Euclidean vector space ℝ d… 
Highly Cited
2012
Highly Cited
2012
Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect
Previous studies have demonstrated that bergamottin (BG), a component of grapefruit juice, is a mechanism-based inactivator of… 
Review
2011
Review
2011
Teleost polarization vision: how it might work and what it might be good for
In this review, we will discuss the recent literature on fish polarization vision and we will present a model on how the retina… 
Highly Cited
2000
Highly Cited
2000
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco‐2 cells and on the activity of cytochrome P450 3A4
The presence of inhibitors of drug efflux transporters, such as P‐glycoprotein (P‐gp), in grapefruit juice (GFJ) was confirmed… 
Highly Cited
1995
Highly Cited
1995
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
Highly Cited
1994
Highly Cited
1994
Biological and genetic characterization of a hemagglutinating coronavirus isolated from a diarrhoeic child
The coronavirus strain HECV‐4408 was isolated from diarrhea fluid of a 6‐year‐old child with acute diarrhea and propagated in… 
Highly Cited
1989
Highly Cited
1989
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Highly Cited
1986
Highly Cited
1986
Mode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovir
9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine (3HM-HBG), (RS)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine ([+/-]2HM-HBG), and cis-9… 
1985
1985
Antiherpes effects and pharmacokinetic properties of 9-(4-hydroxybutyl) guanine and the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine
Three acyclic guanosine analogs with similar structures, the (R) and (S) forms of 9-(3,4-dihydroxybutyl)guanine and 9-(4… 
1983
1983
9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication
A new compound, 9-(3,4-dihydroxybutyl)guanine, has been synthesized and its antiherpes activity determined. 9-(3,4-Dihydroxybutyl… 
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