Skip to search formSkip to main contentSkip to account menu

buciclovir

Known as: BCV, 6H-Purin-6-one, 2-amino-9-(3,4-dihydroxybutyl)-1,9-dihydro-, 9-(3,4-dihydroxybutyl)guanine 
An acyclic guanosine analog with activity against herpes simplex virus (HSV). Buciclovir is phosphorylated to its triphosphate form by HSV thymidine… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Acyclovir
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect
Previous studies have demonstrated that bergamottin (BG), a component of grapefruit juice, is a mechanism-based inactivator of… 
2008
2008
Monitoring ability analysis and qualitative fault diagnosis using hybrid bond graph
Abstract In part I of this work, we lay a foundation for quantitative bond graph-based FDI design of hybrid systems using hybrid… 
2008
2008
Causality assignment and model approximation for quantitative hybrid bond graph-based fault diagnosis
Abstract Bond graph (BG) is an effective tool for modeling complex systems and it has been proven to be useful for fault… 
Highly Cited
1989
Highly Cited
1989
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Highly Cited
1986
Highly Cited
1986
Mode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovir
9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine (3HM-HBG), (RS)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine ([+/-]2HM-HBG), and cis-9… 
1985
1985
Antiherpes effects and pharmacokinetic properties of 9-(4-hydroxybutyl) guanine and the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine
Three acyclic guanosine analogs with similar structures, the (R) and (S) forms of 9-(3,4-dihydroxybutyl)guanine and 9-(4… 
1984
1984
Nucleic acid hybridization, a method to determine effects of antiviral compounds on herpes simplex virus type 1 DNA synthesis.
1983
1983
9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication
A new compound, 9-(3,4-dihydroxybutyl)guanine, has been synthesized and its antiherpes activity determined. 9-(3,4-Dihydroxybutyl… 
1983
1983
Kinetic analysis in cell culture of the reversal of antiherpes activity of nucleoside analogs by thymidine
The inhibition of herpes simplex virus type 1 plaque formation by acyclovir, bromovinyldeoxyuridine, 9-(3,4-dihydroxybutyl… 
1968
1968
Itoic Acid Synthesis in Bacillus subtilis
Under conditions of iron deficiency, strains of Bacillus subtilis produced 2,3-dihydroxybenzoic acid (DHB), 2,3… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)