bropirimine

Known as: ABPP, 2-APPD, 2-amino-5-bromo-6-phenyl-4-(3H)-pyrimidinone 
An oral immunostimulant that causes the body to produce interferon and other substances.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
05101519752017

Papers overview

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2010
2010
We have separated the active polypeptides from aqueous extracts of Achyranthes bidentata Blume (ABPP), a commonly prescribed… (More)
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Highly Cited
2005
Highly Cited
2005
Achieving information content of satisfactory breadth and depth remains a formidable challenge for proteomics. This problem is… (More)
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2003
2003
1. The antitumour agent bropirimine undergoes significant Phase II conjugation in vivo. Incubation of [14C]bropirimine with human… (More)
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1998
1998
OBJECTIVES Bropirimine is an oral immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in… (More)
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1996
1996
OBJECTIVES Bropirimine is an orally administered immunostimulant that has been shown to have activity against carcinoma in situ… (More)
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1994
1994
Imiquimod has been identified as a potent antiviral and antitumor agent in animal models. The biological activity associated with… (More)
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1992
1992
Severe combined immunodeficient (SCID) mice were found to be highly susceptible to murine cytomegalovirus (MCMV) infection… (More)
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1989
1989
The neuritic plaque is a characteristic finding in Alzheimer's disease. A major component of the plaque core is a 4.2 kd… (More)
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1986
1986
2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP) was given to 59 patients in a Phase I study. The agent was selected because it… (More)
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1984
1984
We tested the effect of 2-amino-5-bromo-6 phenyl-4 pyrimidinol (ABPP), an interferon (IFN) inducer, on NK cell cytotoxicity in… (More)
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