brodalumab

 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Over 50 investigational monoclonal antibody (mAb) therapeutics are currently undergoing evaluation in late-stage clinical studies… (More)
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2016
2016
BACKGROUND The interleukin-17 cytokine family plays a central role in psoriasis pathogenesis. OBJECTIVES To evaluate the… (More)
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Highly Cited
2016
Highly Cited
2016
www.thelancet.com Vol 387 January 16, 2016 227 3 Griffi ths CEM, Reich K, Lebwohl M, et al. Comparison of ixekizumab with… (More)
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2016
2016
OBJECTIVES:To assess the safety and efficacy of brodalumab, a human anti-interleukin-17 receptor monoclonal antibody, in patients… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Early clinical studies suggested that the anti-interleukin-17 receptor A monoclonal antibody brodalumab has efficacy… (More)
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2015
2015
OBJECTIVE To evaluate the efficacy and safety of brodalumab, a human monoclonal antibody inhibitor of the interleukin 17 receptor… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND We assessed the efficacy and safety of brodalumab, a human monoclonal antibody against interleukin-17 receptor A… (More)
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2014
2014
BACKGROUND Brodalumab (anti-interleukin-17-receptor antibody) was effective in treating moderate to severe psoriasis in a 12-week… (More)
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Highly Cited
2013
Highly Cited
2013
RATIONALE IL-17 signaling has been implicated in development and persistence of asthma. Cytokine-targeted strategies blocking IL… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND In this phase 2, randomized, double-blind, placebo-controlled, dose-ranging study, we assessed the efficacy and safety… (More)
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