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SummaryTen healthy subjects whose genetic oxidative phenotype had been determined (6 extensive and 4 poor metabolizers of the… Expand The mechanisms for the vascular actions of vasodilatory beta-blockers remain undetermined. For some kinds of beta-blockers, the… Expand Beta blockers are among t.he drugs most commonly used to treat patients with systemic hypertension. Regardless of whether they… Expand We have previously reported that a potent new beta-blocker, tertatolol, when given at therapeutic doses to healthy volunteers… Expand 1 The cardiovascular effects of apamin, a selective blocker of certain calcium‐activated potassium channels, and BRL 34915, a… Expand Bopindolol, an esterified beta-adrenoceptor blocking drug, was administered to nine healthy male volunteers in oral (1 mg and 4… Expand Bopindolol is a potent and specific beta-adrenoceptor antagonist with partial agonist activity. In animal experiments it blocks… Expand Bopindolol has β‐blocking effects for 96 hr despite a 4‐hr t½. To investigate the concentration‐effect relationship after single… Expand The influence of bopindolol monotherapy on blood pressure and plasma lipid fractions was investigated in 24 hypertensive patients… Expand Summary Bopindolol (LT 31–200), a new, long-acting, nonselective β-adrenoceptor blocking agent with partial agonist activity, was… Expand