blood microparticle formation

Known as: microparticle generation, microparticle release 
The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cutting-Edge Analysis of Extracellular Microparticles using ImageStreamX Imaging Flow Cytometry
Interest in extracellular vesicle biology has exploded in the past decade, since these microstructures seem endowed with multiple… (More)
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Highly Cited
2011
Highly Cited
2011
Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts.
OBJECTIVE Circulating microparticles are increased in cardiovascular disease and may themselves promote oxidative stress and… (More)
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Review
2010
Review
2010
Formation of procoagulant microparticles and properties.
The platelet procoagulant response consists of providing a catalytic surface where vitamin K-dependent clotting factors can… (More)
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Highly Cited
2009
Highly Cited
2009
Acid sphingomyelinase activity triggers microparticle release from glial cells
We have earlier shown that microglia, the immune cells of the CNS, release microparticles from cell plasma membrane after ATP… (More)
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Highly Cited
2007
Highly Cited
2007
Inhibition of microparticle release triggers endothelial cell apoptosis and detachment.
Endothelial cell cultures contain caspase 3-containing microparticles (EMP), which are reported to form during or after cell… (More)
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Highly Cited
2006
Highly Cited
2006
Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress.
We describe here the mechanism of platelet adhesion to immobilized von Willebrand factor (VWF) and subsequent formation of… (More)
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Highly Cited
2006
Highly Cited
2006
Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2.
Thrombin exerts pleiotropic effects on endothelial cells, including the release of microparticles (EMPs) that disseminate and… (More)
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Highly Cited
2004
Highly Cited
2004
Statin decreases endothelial microparticle release from human coronary artery endothelial cells: implication for the Rho-kinase pathway.
OBJECTIVE Elevated plasma levels of endothelial microparticles (EMPs) are associated with the presence of clinical… (More)
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Highly Cited
1996
Highly Cited
1996
High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles.
Previous studies have demonstrated that a high level of shear stress can produce platelet aggregation without the addition of any… (More)
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Highly Cited
1989
Highly Cited
1989
Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity.
Activation of human platelets by complement proteins C5b-9 is accompanied by the release of small plasma membrane vesicles… (More)
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