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bisamidine

National Institutes of Health

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Papers overview

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2019
2019
Water, an Essential Element for a Zn(II)-Catalyzed Asymmetric Quinone Diels-Alder Reaction: Multi-selective Construction of Highly Functionalized cis-Decalins.
A Zn(II) complex of a C2-chiral bisamidine-type sp2N bidentate ligand (LR) possessing two dioxolane rings at both ends catalyzes… 
2015
2015
Probing the Relationship between Anti-Pneumocystis carinii Activity and DNA Binding of Bisamidines by Molecular Dynamics Simulations
The anti-Pneumocystis carinii activity of 13 synthetic pentamidine analogs was analyzed. The experimental differences in melting… 
2012
2012
Chiral Zn(II)-Bisamidine Complex as a Lewis-Brønsted Combined Acid Catalyst: Application to Asymmetric Mukaiyama Aldol Reactions of α-Ketoesters
Focusing on the steric and electronic properties of the resonance-stabilized amidine framework, a cationic metal-bisamidine… 
2007
2007
Solution behaviour and biological activity of bisamidine complexes of platinum(II)
A series of platinum(II) amidine complexes were previously prepared with the aim of obtaining a new class of platinum-based… 
Highly Cited
2007
Highly Cited
2007
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations.
Forty three cationic bisbenzofurans were synthesized either by interaction of o-hydroxyaldehydes with alpha-halogenated ketones… 
2007
2007
Indoline derivatives I: synthesis and factor Xa (FXa) inhibitory activities.
A series of bisamidine derivatives each having a ring structure in the center of the molecule was synthesized and their Factor Xa… 
2002
2002
Elongation factor 2 as a target for selective inhibition of protein synthesis in vitro by the novel aromatic biasamidine
The effect of the novel aromatic bisamidine 1 on protein synthesis in cell-free translational system isolated from rat livers was… 
1999
1999
Conformations of trypsin-bound amidine inhibitors of blood coagulant factor Xa by double REDOR NMR and MD simulations.
Double rotational-echo double resonance (double REDOR) has been used to investigate the bound conformations of (13)C,(15)N,(19)F… 
1996
1996
Syntheses and Selective Inhibitory Activities of Terphenyl‐Bisamidines for Serine Proteases
Biphenyl nitriles 5a—c, terphenyl dinitriles 11a—d, and naphthalene‐bis(benzonitrile) 11e were prepared by palladium‐catalyzed… 
Highly Cited
1981
Highly Cited
1981
The structure of CC-1065, a potent antitumor agent and its binding to DNA
The crystal and molecular structure of a potent antitumor agent, CC1065 (C37H33N708), has been determined, and circular dichroism… 
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