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bisamidine

 
National Institutes of Health

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2018
2018
Polyglutamine (polyQ) diseases are a group of dominantly inherited neurodegenerative disorders caused by the expansion of an… Expand
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2015
2015
We report the results of an investigation of the activity of a series of amidine and bisamidine compounds against Staphylococcus… Expand
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2014
2014
Herein we describe the synthesis and antibacterial evaluation of a new, unsymmetrical triaryl bisamidine compound series, [Am… Expand
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2013
2013
With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. We report here the discovery and X… Expand
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2013
2013
The prevalence of drug-resistant bacteria in the clinic has propelled a concerted effort to find new classes of antibiotics that… Expand
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2010
2010
The reactivity of a series of symmetrical chiral Brønsted acids (polar ionic hydrogen-bond donors) follows the counterintuitive… Expand
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2007
2007
The chiral bisamidine 5 has been prepared in just two steps from malonodinitrile. In the monocationic form this compound adopts a… Expand
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2007
2007
Forty three cationic bisbenzofurans were synthesized either by interaction of o-hydroxyaldehydes with alpha-halogenated ketones… Expand
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2004
2004
Despite Nature's longstanding ability to use a proton, the most prevalent Lewis acid, to both activate and orient a substrate… Expand
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1999
1999
A novel series of 2,6-diphenoxypyridines has been designed to inhibit factor Xa, a serine protease strategically located in the… Expand
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