bisamidine
National Institutes of Health
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We report the results of an investigation of the activity of a series of amidine and bisamidine compounds against Staphylococcus…
With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. We report here the discovery and X…
The reactivity of a series of symmetrical chiral Brønsted acids (polar ionic hydrogen-bond donors) follows the counterintuitive…
The chiral bisamidine 5 has been prepared in just two steps from malonodinitrile. In the monocationic form this compound adopts a…
Forty three cationic bisbenzofurans were synthesized either by interaction of o-hydroxyaldehydes with alpha-halogenated ketones…
A series of platinum(II) amidine complexes were previously prepared with the aim of obtaining a new class of platinum-based…
Despite Nature's longstanding ability to use a proton, the most prevalent Lewis acid, to both activate and orient a substrate…
Amidines have long been known to form strong noncovalent complexes with carboxylates and phosphates. However, their interaction…
Biphenyl nitriles 5a—c, terphenyl dinitriles 11a—d, and naphthalene‐bis(benzonitrile) 11e were prepared by palladium‐catalyzed…
The crystal and molecular structure of a potent antitumor agent, CC1065 (C37H33N708), has been determined, and circular dichroism…