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bisamidine

 
National Institutes of Health

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Furans

Papers overview

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2015
2015
Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compounds.
Herein, we describe the antifungal evaluation of 43 bisamidine compounds, of which 26 are new, having the scaffold [Am]-[HetAr… Expand
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Highly Cited
2012
Highly Cited
2012
Antibacterial drug leads targeting isoprenoid biosynthesis
With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. We report here the discovery and X… Expand
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Highly Cited
2010
Highly Cited
2010
Bifunctional asymmetric catalysis: amplification of Brønsted basicity can orthogonally increase the reactivity of a chiral Brønsted acid.
The reactivity of a series of symmetrical chiral Brønsted acids (polar ionic hydrogen-bond donors) follows the counterintuitive… Expand
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2007
2007
Synthesis of C2-symmetric bisamidines: a new type of chiral metal-free Lewis acid analogue interacting with carbonyl groups.
The chiral bisamidine 5 has been prepared in just two steps from malonodinitrile. In the monocationic form this compound adopts a… Expand
Highly Cited
2007
Highly Cited
2007
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations.
Forty three cationic bisbenzofurans were synthesized either by interaction of o-hydroxyaldehydes with alpha-halogenated ketones… Expand
2006
2006
Solution behaviour and biological activity of bisamidine complexes of platinum(II)
A series of platinum(II) amidine complexes were previously prepared with the aim of obtaining a new class of platinum-based… Expand
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Highly Cited
2004
Highly Cited
2004
Chiral proton catalysis: a catalytic enantioselective direct aza-Henry reaction.
Despite Nature's longstanding ability to use a proton, the most prevalent Lewis acid, to both activate and orient a substrate… Expand
1999
1999
Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.
A novel series of 2,6-diphenoxypyridines has been designed to inhibit factor Xa, a serine protease strategically located in the… Expand
1996
1996
Syntheses and Selective Inhibitory Activities of Terphenyl‐Bisamidines for Serine Proteases
Biphenyl nitriles 5a—c, terphenyl dinitriles 11a—d, and naphthalene‐bis(benzonitrile) 11e were prepared by palladium‐catalyzed… Expand
Highly Cited
1981
Highly Cited
1981
The structure of CC-1065, a potent antitumor agent and its binding to DNA
The crystal and molecular structure of a potent antitumor agent, CC1065 (C37H33N708), has been determined, and circular dichroism… Expand
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