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bisabolangelone

National Institutes of Health

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Sesquiterpenes

Papers overview

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2018
2018
Pharmacokinetics and tissue distribution study of bisabolangelone from Angelicae Pubescentis Radix in rat using LC-MS/MS.
A sensitive and accurate LC-MS/MS method was established for quantifying bisabolangelone in rat plasma and tissues… 
2014
2014
Ultra high performance liquid chromatography with photodiode array detector and quadrupole time-of-flight tandem mass spectrometry coupled with discriminant analysis to evaluate Angelicae pubescentis…
A rapid and effective method was developed for the qualitative and quantitative analysis of the major chemical constituents in… 
2013
2013
cAMP-binding site of PKA as a molecular target of bisabolangelone against melanocyte-specific hyperpigmented disorder.
Microphthalmia-associated transcription factor (MITF) is inducible in response to cAMP and has a pivotal role in the melanocyte… 
2012
2012
Melanogenesis inhibitory bisabolane-type sesquiterpenoids from the roots of Angelica koreana.
2012
2012
Simultaneous analysis of six major compounds in Osterici Radix and Notopterygii Rhizoma et Radix by HPLC and discrimination of their origins from chemical fingerprint analysis
Osterici Radix, the dried roots of Ostericum koreanum Maximowicz, has long been used to treat cold, headache and arthralgia in… 
Highly Cited
2011
Highly Cited
2011
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.
Highly Cited
2010
Highly Cited
2010
Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells.
2008
2008
Simultaneous Determination of Biological Marker Compounds in Ostericum koreanum by HPLC Method and Discrimination by Principal Component Analysis
An analytical method for the simultaneous determination of four biological marker compounds including bisabolangelone… 
2006
2006
Toxicity of bisabolangelone from Ostericum koreanum roots to Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae).
The acaricidal activity of materials derived from the roots of Ostericum koreanum (Apiaceae) toward adults of Dermatophagoides… 
2002
2002
Inhibitors of 5alpha -reductase type I in LNCaP cells from the roots of Angelica koreana.
A prenylated coumarin, osthenol (1) and a sesquiterpene, bisabolangelone (2) have been isolated as active principles with 5alpha… 
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