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bilirubin uridine-diphosphoglucuronosyl transferase 1A10

Known as: UDP-glucuronosyltransferase 1A10, human, UGT1A10 
National Institutes of Health

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Glucuronosyltransferase

Papers overview

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2017
2017
Evaluation of Expression and Glycosylation Status of UGT1A10 in Supersomes and Intestinal Epithelial Cells with a Novel Specific UGT1A10 Monoclonal Antibody
UDP-Glucuronosyltransferases (UGTs) are major phase II drug-metabolizing enzymes. Each member of the UGT family exhibits a unique… 
2015
2015
Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10
OTS167 is a potent maternal embryonic leucine zipper kinase inhibitor undergoing clinical testing as antineoplastic agent. We… 
2013
2013
Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
The acridinone derivates 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8… 
2012
2012
Highly variable pH effects on the interaction of diclofenac and indomethacin with human UDP-glucuronosyltransferases.
2011
2011
Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens
2010
2010
How Many and Which Amino Acids Are Responsible for the Large Activity Differences between the Highly Homologous UDP-Glucuronosyltransferases (UGT) 1A9 and UGT1A10?
The amino acid sequences of the human UDP-glucuronosyltransferases (UGTs) 1A9 and 1A10 are 93% identical, yet there are large… 
2009
2009
Key Amino Acid Residues Responsible for the Differences in Substrate Specificity of Human UDP-Glucuronosyltransferase (UGT)1A9 and UGT1A8
Human UDP-glucuronosyltransferase (UGT)1A9 is one of the major isoforms in liver and extrahepatic tissues, catalyzing the… 
2009
2009
Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.
Highly Cited
2007
Highly Cited
2007
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10.
The UDP-glucuronosyltransferase (UGT) 1A10 is an extra-hepatic enzyme that plays an important role in the glucuronidation of a… 
2002
2002
Structure-activity relationship in O-glucuronidation of indolocarbazole analogs.
The glucuronidation of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)5H-indolo[2,3-a]pyrrolo[3,4-c… 
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