Skip to search formSkip to main contentSkip to account menu

bicifadine

Known as: ( -)-1-p-Tolyl-3-azabicyclo(3.1.0)hexane, (RS)-1-(4-Methylphenyl)-3-azabicyclo(3.1.0)hexan 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Bridged Bicyclo Compounds, Heterocyclic
bicifadine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Pharmacokinetics, Disposition, and Metabolism of Bicifadine in the Mouse, Rat, and Monkey
Bicifadine [DOV 220,075; (±)-1-(4-methylphenyl)-3-azabicyclo[3.1.0]-hexane HCl)] is a non-narcotic analgesic that is effective in… 
2008
2008
Pharmacokinetics, Disposition, and Metabolism of Bicifadine in Humans
Bicifadine [DOV 220,075; (±)-1-(4-methylphenyl)-3-azabicyclo-[3.1.0]hexane HCl)] is a non-narcotic analgesic that has proven to… 
Highly Cited
2007
Highly Cited
2007
Characterization of the Antinociceptive Actions of Bicifadine in Models of Acute, Persistent, and Chronic Pain
Bicifadine (1-p-tolyl-3-azabicyclo[3.1.0]hexane) inhibits monoamine neurotransmitter uptake by recombinant human transporters in… 
2007
2007
In Vitro Metabolism of the Analgesic Bicifadine in the Mouse, Rat, Monkey, and Human
The in vitro metabolism of [14C]bicifadine by hepatic microsomes and hepatocytes from mouse, rat, monkey, and human was compared… 
2005
2005
Bicifadine nonopioid analgesic : USAN norepinephrine transporter inhibitor serotonin transporter inhibitor NMDA antagonist
Although a multitude of agents have been developed and marketed for pain management, an effective treatment for chronic pain has… 
2003
2003
Manufacturing method of bicifadine
Bicifadine and a dosage form and the oral administration of a composition comprising a salt thereof, composition and a modified… 
2003
2003
Preparation de bicifadine
L'invention concerne une methode et une composition destinees a l'administration orale d'une composition a forme posologique… 
Highly Cited
1987
Highly Cited
1987
Allosteric Interaction Between the Site Labeled by [3H]Imipramine and the Serotonin Transporter in Human Platelets
Abstract: The nature of interaction between the site labeled by [3H]imipramine (IMI) and the 5‐hydroxytryptamine (5‐HT, serotonin… 
1982
1982
Bicifadine: non-narcotic analgesic activity of 1-aryl-3-azabicyclo[3.1.0] hexanes.
1982
1982
Bicifadine: non-narcotic analgesic activity of 1-aryl-3-azabicyclo[3.1.0] hexanes.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)