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beta-chimaerin

Known as: beta 2-chimaerin, beta2-chimaerin 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

CHN2 protein, human

Broader (1)

Neoplasm Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways.
2010
2010
p23/Tmp21 Differentially Targets the Rac-GAP β2-Chimaerin and Protein Kinase C via Their C1 Domains
The ER/Golgi protein p23/Tmp21 acts as a C1 domain-docking protein that mediates perinuclear translocation of β-chimaerin. C1… 
2009
2009
T Cell Receptor-dependent Tyrosine Phosphorylation of β2-Chimaerin Modulates Its Rac-GAP Function in T Cells*
The actin cytoskeleton has an important role in the organization and function of the immune synapse during antigen recognition… 
2006
2006
β2-chimaerin provides a diacylglycerol-dependent mechanism for regulation of adhesion and chemotaxis of T cells
The small GTPase Rac contributes to regulation of cytoskeletal rearrangement during chemokine-induced lymphocyte adhesion and… 
Highly Cited
2004
Highly Cited
2004
Structural Mechanism for Lipid Activation of the Rac-Specific GAP, β2-Chimaerin
Highly Cited
2003
Highly Cited
2003
Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor.
The regulation and function of beta2-chimaerin, a novel receptor for the phorbol ester tumour promoters and the second messenger… 
2003
2003
Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain.
The biological and functional properties of beta2-chimaerin, a novel phorbol ester/diacylglycerol receptor unrelated to protein… 
Highly Cited
2002
Highly Cited
2002
Chimaerins, Novel Non-protein Kinase C Phorbol Ester Receptors, Associate with Tmp21-I (p23)
The regulation and function of chimaerins, a family of “non-protein kinase C” (PKC) phorbol ester/diacylglycerol receptors with… 
2002
2002
Interaction of the novel anthracycline antitumor agent N-benzyladriamycin-14-valerate with the C1-regulatory domain of protein kinase C: structural requirements, isoform specificity, and correlation…
Anthracycline antibiotics like doxorubicin (DOX) are known to exert their antitumor effects primarily via DNA intercalation and… 
Highly Cited
2001
Highly Cited
2001
Phorbol Esters and Related Analogs Regulate the Subcellular Localization of β2-Chimaerin, a Non-protein Kinase C Phorbol Ester Receptor*
The novel phorbol ester receptor β2-chimaerin is a Rac-GAP protein possessing a single copy of the C1 domain, a 50-amino acid… 
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