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beta catenin
Known as:
CTNNB1
, beta Catenin [Chemical/Ingredient]
, Cadherin-Associated Protein, Beta 1 (88kD)
Â
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Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and…Â
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Topic mentions per year
Topic mentions per year
1991-2017
0
200
400
600
1991
2017
Related topics
Related topics
27 relations
ALK Pathway
CTNNB1 gene
Cadherins
Catenins
(More)
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
beta catenin
Signal Transduction
physiological aspects
agonists
Colorectal Carcinoma
Cell Adhesion
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
Amanda J. Mikels
,
Roel Nusse
PLoS biology
2006
The Wnts comprise a large class of secreted proteins that control essential developmental processes such as embryonic patterning…Â
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Highly Cited
2005
Highly Cited
2005
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis.
Timothy F. Day
,
Xizhi Guo
,
Lisa J. Garrett-Beal
,
Yingzi Yang
Developmental cell
2005
Chondrocytes and osteoblasts are two primary cell types in the skeletal system that are differentiated from common mesenchymal…Â
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Highly Cited
2005
Highly Cited
2005
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Theo P. Hill
,
Daniela Später
,
Makoto Mark Taketo
,
Walter Birchmeier
,
Christine Hartmann
Developmental cell
2005
Osteoblasts and chondrocytes are involved in building up the vertebrate skeleton and are thought to differentiate from a common…Â
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Highly Cited
1999
Highly Cited
1999
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.
O Tetsu
,
Francis McCormick
Nature
1999
Mutations in the adenomatous polyposis coli (APC) tumour-suppressor gene occur in most human colon cancers. Loss of functional…Â
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Highly Cited
1999
Highly Cited
1999
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
Marat Shtutman
,
Jacob Zhurinsky
,
+4 authors
Aaron Ben-Ze'ev
Proceedings of the National Academy of Sciences…
1999
beta-Catenin plays a dual role in the cell: one in linking the cytoplasmic side of cadherin-mediated cell-cell contacts to the…Â
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Highly Cited
1998
Highly Cited
1998
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
J. Behrens
,
Boris Jerchow
,
+6 authors
Walter Birchmeier
Science
1998
Control of stability of beta-catenin is central in the wnt signaling pathway. Here, the protein conductin was found to form a…Â
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Highly Cited
1997
Highly Cited
1997
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
Patrice J. Morin
,
Alicia Sparks
,
+4 authors
Kenneth W. Kinzler
Science
1997
Inactivation of the adenomatous polyposis coli (APC) tumor suppressor gene initiates colorectal neoplasia. One of the biochemical…Â
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Highly Cited
1997
Highly Cited
1997
beta-catenin is a target for the ubiquitin-proteasome pathway.
H G Aberle
,
Anand Mathias Bauer
,
Jörg Stappert
,
Anna Kispert
,
Rolf Kemler
The EMBO journal
1997
beta-catenin is a central component of the cadherin cell adhesion complex and plays an essential role in the Wingless/Wnt…Â
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Highly Cited
1996
Highly Cited
1996
Functional interaction of beta-catenin with the transcription factor LEF-1.
J. Behrens
,
Jens Peter von Kries
,
+4 authors
Walter Birchmeier
Nature
1996
The cytoplasmic proteins beta-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell…Â
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Highly Cited
1993
Highly Cited
1993
Association of the APC gene product with beta-catenin.
Bonnee Rubinfeld
,
Bruno Feres de Souza
,
+5 authors
Pavlos Polakis
Science
1993
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and…Â
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