FAQ

beta catenin

Known as: CTNNB1, beta Catenin [Chemical/Ingredient], Cadherin-Associated Protein, Beta 1 (88kD) 
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and… (More)

Topic mentions per year

Topic mentions per year

1991-2017
020040060019912017

Related topics

Related topics

27 relations
ALK PathwayCTNNB1 geneCadherinsCatenins
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
beta catenin
Signal Transduction
physiological aspects
agonists
Colorectal Carcinoma
Cell Adhesion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
The Wnts comprise a large class of secreted proteins that control essential developmental processes such as embryonic patterning… (More)
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Highly Cited
2005
Highly Cited
2005
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis.
Chondrocytes and osteoblasts are two primary cell types in the skeletal system that are differentiated from common mesenchymal… (More)
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Highly Cited
2005
Highly Cited
2005
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Osteoblasts and chondrocytes are involved in building up the vertebrate skeleton and are thought to differentiate from a common… (More)
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Highly Cited
1999
Highly Cited
1999
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.
Mutations in the adenomatous polyposis coli (APC) tumour-suppressor gene occur in most human colon cancers. Loss of functional… (More)
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Highly Cited
1999
Highly Cited
1999
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
beta-Catenin plays a dual role in the cell: one in linking the cytoplasmic side of cadherin-mediated cell-cell contacts to the… (More)
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Highly Cited
1998
Highly Cited
1998
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Control of stability of beta-catenin is central in the wnt signaling pathway. Here, the protein conductin was found to form a… (More)
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Highly Cited
1997
Highly Cited
1997
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
Inactivation of the adenomatous polyposis coli (APC) tumor suppressor gene initiates colorectal neoplasia. One of the biochemical… (More)
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Highly Cited
1997
Highly Cited
1997
beta-catenin is a target for the ubiquitin-proteasome pathway.
beta-catenin is a central component of the cadherin cell adhesion complex and plays an essential role in the Wingless/Wnt… (More)
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Highly Cited
1996
Highly Cited
1996
Functional interaction of beta-catenin with the transcription factor LEF-1.
The cytoplasmic proteins beta-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell… (More)
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Highly Cited
1993
Highly Cited
1993
Association of the APC gene product with beta-catenin.
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and… (More)
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