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CTNNB1 gene

Known as: CTNNB1, Catenin (Cadherin-Associated Protein), Beta 1, 88kDa Gene, CADHERIN-ASSOCIATED PROTEIN, BETA 
This gene is involved in signal transduction and regulation of transcription.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The canonical Wnt/β-catenin signaling pathway, an important modulator of progenitor cell proliferation and differentiation, is… Expand
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Highly Cited
2008
Highly Cited
2008
Desmoid fibromatosis is a rare, nonmetastatic neoplasm marked by local invasiveness and relentless recurrence. Molecular… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Axin2/Conductin/Axil and its ortholog Axin are negative regulators of the Wnt signaling pathway, which promote the… Expand
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Highly Cited
2002
Highly Cited
2002
The Wnt pathway controls numerous developmental processes via the beta-catenin-TCF/LEF transcription complex. Deregulation of the… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract As a component of adherens junctions and the Wnt signaling pathway, β-catenin binds cadherins, Tcf family transcription… Expand
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Highly Cited
1999
Highly Cited
1999
Ectopic expression of certain Wnt genes in mouse mammary tissue is tumorigenic, and mutations that stabilize β‐catenin are found… Expand
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Highly Cited
1999
Highly Cited
1999
Mutations in the adenomatous polyposis coli or beta-catenin gene lead to cytosolic accumulation of beta-catenin and, subsequently… Expand
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Highly Cited
1996
Highly Cited
1996
The cytoplasmic proteins beta-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell… Expand
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Highly Cited
1996
Highly Cited
1996
Vertebrate beta-catenin and Drosophila Armadillo share structural similarities suggesting that beta-catenin, like Armadillo, has… Expand
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Highly Cited
1993
Highly Cited
1993
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and… Expand
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