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CTNNB1 gene

Known as: CTNNB1, Catenin (Cadherin-Associated Protein), Beta 1, 88kDa Gene, CADHERIN-ASSOCIATED PROTEIN, BETA 
This gene is involved in signal transduction and regulation of transcription.
National Institutes of Health

Related topics

Related topics

19 relations
Beta-Catenin-Activated Hepatocellular AdenomaCell AdhesionColorectal CarcinomaHepatoblastoma

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CTNNB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Association of Genetic Variation in Genes Implicated in the β-Catenin Destruction Complex with Risk of Breast Cancer
Aberrant Wnt/β-catenin signaling leading to nuclear accumulation of the oncogene product β-catenin is observed in a wide spectrum… 
Highly Cited
2007
Highly Cited
2007
Canonical Wnt signaling transiently stimulates proliferation and enhances neurogenesis in neonatal neural progenitor cultures.
Highly Cited
2007
Highly Cited
2007
Expression of oncofetal RNA‐binding protein CRD‐BP/IMP1 predicts clinical outcome in colon cancer
The oncofetal CRD‐BP/IMP1 RNA binding protein regulates posttranscriptionally a handful of RNA transcripts, implicated in cell… 
2007
2007
Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
BACKGROUND & AIMS We report a patient of Indian descent with parental consanguinity, who developed 10 carcinomas and 35… 
2006
2006
Intracellular expression of the T-cell factor-1 RNA aptamer as an intramer
T-cell factor (TCF)-1 protein forms the transcriptional complex with β-catenin and regulates the expression of diverse target… 
Highly Cited
2004
Highly Cited
2004
APC mutations are infrequent but present in human lung cancer.
Highly Cited
2004
Highly Cited
2004
Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line.
Beta-catenin is an essential element for the transcriptional activation of target genes in the Wnt signaling cascade and is also… 
2004
2004
Molecular alterations associated with cyclin d1 overexpression in endometrial cancer
Cyclin D1 is frequently overexpressed in human neoplasias by gene rearrangement and amplification. In addition, Ras, PTEN and… 
Highly Cited
1999
Highly Cited
1999
beta-catenin expression pattern in stage I and II ovarian carcinomas : relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome.
The immunohistochemical expression pattern of beta-catenin has been correlated with beta-catenin gene mutations… 
Highly Cited
1999
Highly Cited
1999
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
The majority of human colorectal cancers have elevated beta-catenin/TCF regulated transcription due to either inactivating… 
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